Z-321 manufacturers
- Z-321
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- $2500.00
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2026-04-21
- CAS:130849-58-0
- Purity:
- Supply Ability: 10g
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| Product Name: | Z-321 | | Synonyms: | Z-321;Thiazolidine, 3-[(2,3-dihydro-1H-inden-2-yl)acetyl]-4-(1-pyrrolidinylcarbonyl)-, (4R)- (9CI);Z321,Z 321 | | CAS: | 130849-58-0 | | MF: | C19H24N2O2S | | MW: | 344.47 | | EINECS: | | | Product Categories: | | | Mol File: | 130849-58-0.mol |  |
| | Z-321 Chemical Properties |
| Boiling point | 588.8±50.0 °C(Predicted) | | density | 1.265±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 250 mg/mL (725.75 mM) | | form | Solid | | pka | -0.84±0.20(Predicted) | | color | White to off-white |
| | Z-321 Usage And Synthesis |
| Uses | Z-321, is a prolylendopeptidase (PEP) inhibitor. | | in vivo | Z-321 is a prolylendopeptidase (PEP) inhibitor. In the 100 or 200 mg/kg Z-321-treated groups, mean lordosis quotient (LQ) decreases after administration. However, there is no statistical difference among the values before and after. In contrast, the mean LQ in the 300 mg/kg Z-321-treated females is lower than that before injection (P<0.005). Furthermore, when compare to that in the vehicle-treated control group, mean LQ is also significantly lower (p<0.05). The incidence of soliciting behavior decreases after treatment with 300 mg/kg Z-321, when compare to that before treatment, but there is no statistical difference. The present study also demonstrates that 300 mg/kg Z-321 is effective in inhibiting lordosis behavior without disturbance of locomotor activity[1]. |
| | Z-321 Preparation Products And Raw materials |
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