S(-)-RACLOPRIDE L-TARTRATE manufacturers
- Raclopride
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- $45.00
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2026-06-02
- CAS:84225-95-6
- Purity: 99.17%
- Supply Ability: 10g
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| | S(-)-RACLOPRIDE L-TARTRATE Basic information |
| Product Name: | S(-)-RACLOPRIDE L-TARTRATE | | Synonyms: | (S)-3,5-dichloro-N-((1-ethylpyrrolidin
-2-yl)methyl)-2-hydroxy-6-
methoxybenzamide (2R,3R)
-2,3-dihydroxysuccinate;(2S)-3,5-DICHLORO-N-[(1-ETHYL-2-PYRROLIDINYL)-METHYL]-6- METHOXYSALICYLAMIDE;BENZAMIDE, 3,5-DICHLORO-N-[[(2S)-1-ETHYL-2-PYRROLIDINYL]METHYL]-2-HYDROXY-6-METHOXY-;3,5-Dichloro-N-[(2S)-1-ethyl-2-pyrrolidinyl]-2-hydroxy-6-methoxybenzamide;FLA-870;3,5-Dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxy-6-hydroxybenzamide;3,5-Dichloro-N-[[(2S)-1-ethylpyrrolidine-2α-yl]methyl]2-hydroxy-6-methoxybenzamide;(-)-(S)-3,5-Dichlor-N-((1-ethyl-2-pyrrolidinyl)methyl)-6-hydroxy-o-anisamid | | CAS: | 84225-95-6 | | MF: | C15H20Cl2N2O3 | | MW: | 347.24 | | EINECS: | | | Product Categories: | Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;Dopamine receptor | | Mol File: | 84225-95-6.mol |  |
| | S(-)-RACLOPRIDE L-TARTRATE Chemical Properties |
| Melting point | 52.0 to 56.0 °C | | Boiling point | 420.3±45.0 °C(Predicted) | | density | 1.288±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,2-8°C | | solubility | H2O: 89 mg/mL | | form | solid | | pka | 5.93±0.50(Predicted) | | color | white | | InChI | 1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m1/s1 | | InChIKey | WAOQONBSWFLFPE-SECBINFHSA-N | | SMILES | Clc1c(c(c(c(c1)Cl)O)C(=O)NC[C@@H]2N(CCC2)CC)OC |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | CV3465000 | | HS Code | 2933.99.8290 | | Storage Class | 11 - Combustible Solids |
| | S(-)-RACLOPRIDE L-TARTRATE Usage And Synthesis |
| Description | Raclopride is a selective dopamine D2/D3 receptor antagonist with Ki values of 1.8, 3.5, 2,400, and 18,000 nM for D2, D3, D4, and D1 receptors, respectively. It passes the blood brain barrier and can be used in in vivo binding and autoradiography studies of the dopamine system under normal and pathological conditions such as Huntington’s disease. | | Chemical Properties | Yellowish solid | | Uses | A labelled dopamine receptor | | Uses | neuroleptic;selective dopamine D1/D2 receptors antagonist | | Uses | Raclopride is a potent D2DR/D3DR antagonist. | | Definition | ChEBI: 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide is a member of salicylamides. | | Biological Activity | Selective and potent dopamine D 2 /D 3 receptor antagonist (K i values are 1.8, 3.5, 2400 and 18000 nM for D 2 , D 3 , D 4 and D 1 receptors respectively). Centrally active following systemic administration in vivo . | | storage | Store at -20°C | | References | [1] M S LIDOW. Dopamine D2 receptors in the cerebral cortex: distribution and pharmacological characterization with [3H]raclopride.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1989, 86 16: 6412-6416. DOI: 10.1073/pnas.86.16.6412
[2] GINOVART N. Imaging the dopamine system with in vivo [11C]raclopride displacement studies: understanding the true mechanism.[J]. Molecular Imaging and Biology, 2005, 7 1: 45-52. DOI: 10.1007/s11307-005-0932-0 |
| | S(-)-RACLOPRIDE L-TARTRATE Preparation Products And Raw materials |
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