- (S)-(-)-Perillyl alcohol 96%
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- $15.00 / 1KG
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2021-07-02
- CAS:18457-55-1
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | (-)-PERILLYL ALCOHOL Basic information |
| Product Name: | (-)-PERILLYL ALCOHOL | | Synonyms: | Perycorolle;[(4S)-4-(prop-1-en-2-yl)cyclohex-1-en-1-yl]methanol;FEMA 2664;(-)-PERILLYL ALCOHOL 90+%;(-)-PERILLYL ALCOHOL 98+%;(S)-4-Isopropenyl-1-cyclohexenylmethanol, (S)-p-Mentha-1,8-dien-7-ol;(S)-4-(1-Methylethenyl)-1-cyclohexene-1-methanol;(S)-p-Mentha-1,8(9)-dien-7-ol | | CAS: | 18457-55-1 | | MF: | C10H16O | | MW: | 152.23 | | EINECS: | 629-611-6 | | Product Categories: | | | Mol File: | 18457-55-1.mol |  |
| | (-)-PERILLYL ALCOHOL Chemical Properties |
| alpha | -101o (NEAT) | | Boiling point | 119-121 °C11 mm Hg(lit.) | | density | 0.96 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.501 | | Fp | >230 °F | | storage temp. | 2-8°C | | solubility | Chloroform (Sparingly), Methanol (Sparingly) | | form | Liquid | | pka | 14.85±0.10(Predicted) | | color | Colourless | | Specific Gravity | 0.960 | | Optical Rotation | [α]22/D 88°, c = 1 in methanol | | biological source | synthetic | | BRN | 2501605 | | InChI | 1S/C10H16O/c1-8(2)10-5-3-9(7-11)4-6-10/h3,10-11H,1,4-7H2,2H3/t10-/m1/s1 | | InChIKey | NDTYTMIUWGWIMO-SNVBAGLBSA-N | | SMILES | CC(=C)[C@H]1CCC(CO)=CC1 | | LogP | 3.077 (est) | | CAS DataBase Reference | 18457-55-1(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 37/38-41-36/37/38 | | Safety Statements | 26-39-36 | | WGK Germany | 3 | | RTECS | OS8395000 | | F | 10 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | (-)-PERILLYL ALCOHOL Usage And Synthesis |
| Description | (–)-Perillyl alcohol is a monoterpene alcohol that has been found in lavender essential oil and has diverse biological activities. It reduces production of hydroperoxidienes and thiobarbituric acid reactive substances (TBARS) in vitro in a concentration-dependent manner. (–)-Perillyl alcohol inhibits PANC-1 pancreatic carcinoma cell and H-Ras-transformed fibroblast growth when used at a concentration of 1 mM. It also inhibits the growth of P. aeruginosa, E. coli, S. aureus, and C. albicans (MICs = 480-2,900 ppm). | | Uses | (-)-Perillyl Alcohol is a monoterpene that induces apoptosis in colon tumor cells. Also, it is used in preparation of terpene-vanilloid conjugates as anti-inflammatory agents. | | Definition | ChEBI: (S)-(-)-perillyl alcohol is a perillyl alcohol in which the chiral centre has S configuration. It is an enantiomer of a (R)-(+)-perillyl alcohol. | | General Description | (S)-(-)-Perillyl alcohol is a monoterpenoid compound found in the essential oils of cherries, lavender and spearmint. It shows potent anticancer activity. | | References | [1] CLARISSA GERHUSER. Mechanism-based in vitro screening of potential cancer chemopreventive agents[J]. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2003, 523: Pages 163-172. DOI: 10.1016/s0027-5107(02)00332-9
[2] GIUSEPPE RUBERTO Maria T B. Antioxidant activity of selected essential oil components in two lipid model systems[J]. Food Chemistry, 2000, 69 2: Pages 167-174. DOI: 10.1016/s0308-8146(99)00247-2
[3] J KARLSON. Inhibition of tumor cell growth by monoterpenes in vitro: evidence of a Ras-independent mechanism of action.[J]. Anti-Cancer Drugs, 1996, 7 4: 422-429. DOI: 10.1097/00001813-199606000-00008
[4] SHANE G. GRIFFIN. The role of structure and molecular properties of terpenoids in determining their antimicrobial activity[J]. Flavour and Fragrance Journal, 1999, 14 5: 322-332. DOI: 10.1002/(sici)1099-1026(199909/10)14:5<322::aid-ffj837>3.0.co;2-4 |
| | (-)-PERILLYL ALCOHOL Preparation Products And Raw materials |
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