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| | TETRAHYDROFURAN-D8 Basic information |
| Product Name: | TETRAHYDROFURAN-D8 | | Synonyms: | Tetrahydrofuran-d8,for NMR,packaged in 0.75 ml ampules, 99.5 atom % D;Tetrahydrofuran-d8, 99.5% (Isotopic);Tetrahydrofuran-d8, 100%(Isotopic);Tetrahydrofuran-d8, packaged in 0.75 ml ampoules, 99.5 atom % D, for NMR;Tetrahydrofuran-D8, 99.5 atoM % D, for NMR 1ML;Octadeuterotetrahydrofuran
Deuterated Tetrahydrofuran;Tetrahydrofuran-d;Tetrahydrofuran-d8, for NMR, packaged in 0.75 Ml aMpoules, 99.5 atoM % D | | CAS: | 1693-74-9 | | MF: | C4D8O | | MW: | 80.16 | | EINECS: | 216-898-4 | | Product Categories: | Aldrich High Purity NMR Solvents for Routine NMR;High Throughput NMR;Labware;Routine NMR;Solvents for High Throughput NMR;Tubes and Accessories;Tetrahydrofuran-d8;Alphabetical Listings;NMR;NMR Solvents;NMR Solvents and Reagents;Solvent by Application;Solvent by Type;Solvents;Spectroscopy Solvents (IR;Stable Isotopes;T;Tetrahydrofuran (THF);UV/Vis) | | Mol File: | 1693-74-9.mol |  |
| | TETRAHYDROFURAN-D8 Chemical Properties |
| Melting point | −106 °C(lit.) | | Melting point | -108,5°C | | Boiling point | 66°C | | Boiling point | 65-66 °C(lit.) | | density | 0.985 g/mL at 25 °C(lit.) | | density | d = 0,99 | | refractive index | n20/D 1.403(lit.) | | Fp | 1 °F | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Liquid | | color | Colorless | | Specific Gravity | 0.99 | | Water Solubility | Soluble in water. | | BRN | 111854 | | Henry's Law Constant | 2.3×10-1 mol/(m3Pa) at 25℃, Hiatt (2013) | | Stability: | Stable. Incompatible with strong oxidizing agents, strong reducing agents, strong bases, oxygen. May generate peroxides in storage if in contact with air. Highly flammable. Store under nitrogen. Hazardous polymerisation may occur. | | InChI | 1S/C4H8O/c1-2-4-5-3-1/h1-4H2/i1D2,2D2,3D2,4D2 | | InChIKey | WYURNTSHIVDZCO-SVYQBANQSA-N | | SMILES | [2H]C1([2H])OC([2H])([2H])C([2H])([2H])C1([2H])[2H] | | CAS DataBase Reference | 1693-74-9(CAS DataBase Reference) | | EPA Substance Registry System | Furan-2,3,4,5-d4, tetrahydro-d4- (1693-74-9) |
| Hazard Codes | F,Xn,Xi | | Risk Statements | 11-19-36/37-40 | | Safety Statements | 16-29-33-46-37-36-13-36/37 | | RIDADR | UN 2056 3/PG 2 | | WGK Germany | 3 | | RTECS | LU5950000 | | Autoignition Temperature | 215 °C | | HS Code | 2845 90 10 | | HazardClass | 3 | | PackingGroup | II | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 4 Oral
Carc. 2
Eye Irrit. 2
Flam. Liq. 2
STOT SE 3 | | Toxicity | LD50 orally in Rabbit: 1650 mg/kg |
| | TETRAHYDROFURAN-D8 Usage And Synthesis |
| Chemical Properties | colourless liquid with an ether-like odour | | Uses | Tetrahydrofuran-d_8 is a deuterated THF that is used in various synthesis reactions and also used as a precursor for various polymers. | | Definition | ChEBI: Oxolane-d8 is a deuterated compound, a cyclic ether, a member of oxolanes, a saturated organic heteromonocyclic parent and a volatile organic compound. | | General Description | Tetrahydrofuran-d8 may be used as a solvent in the synthesis of deuteriotris[bis(trimethylsilyl)amido]thorium and deuteriotris[bis(trimethylsiiyl)amido]uranium. | | Synthesis | Tetrahydrofuran-d8 was prepared from the exchange of tetrahydrofuran with heavy water catalyzed by a transition metal: a CD3OD mixture of tetrahydrofuran (0.22 mmol) and pyrene-imidazolylidene-iridium(III) complex (2 mol% based on the metal) was heated in a Schlenk tube equipped with a Teflon cap at 100C. AgOTf (8.8 10-3 mmol) was added to the solution. After 12 h, a 50-L aliquot was withdrawn from the reaction vessel. An aliquot was added to an NMR tube containing 0.6 mL of CDCl3. Highly substituted tetrahydrofuran-d8 was obtained using a standard capillary consisting of a solution of ferrocene in CDCl3 (0.025 mg L-1) and the deuteration level was monitored by 1H NMR. |
| | TETRAHYDROFURAN-D8 Preparation Products And Raw materials |
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