2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE

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Products Intro: Product Name:Hexahydro-pyrrolo[3,4-c]pyrrole-2-carboxylic acid tert-butyl ester
CAS:141449-85-6
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Nanjing ChemLin Chemical Industry Co., Ltd.
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Products Intro: CAS:141449-85-6
Purity:95% Package:g-Kg
Company Name: Alchem Pharmtech,Inc.
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Products Intro: Product Name:tert-Butyl hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate
CAS:141449-85-6
Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-01383
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Products Intro: Product Name:2-Boc-Hexahydro-Pyrrolo[3,4-C]Pyrrole
CAS:141449-85-6
Purity:0.98 Package:1g;5g;25g;100;500g
Company Name: CONIER CHEM AND PHARMA LIMITED
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Products Intro: Product Name:2-boc-hexahydropyrrolo(3,4-c)pyrrole
CAS:141449-85-6
Purity:0.99 Package:1kg

2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE manufacturers

2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE Basic information
Product Name:2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE
Synonyms:HEXAHYDRO-PYRROLO[3,4-C]PYRROLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER;2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE;2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE HYDROCHLORIDE;2-Boc-hexahydro-pyrrpol[3,4-c]pyrrole;Pyrrolo[3,4-c]Pyrrole-2(1H)-Ca;2-Boc-octahydropyrrolo[3,4-c]pyrrole;4-c]pyrrole-2(1H)-carboxylate;tert-butyl hexahydropyrrolo[3
CAS:141449-85-6
MF:C11H20N2O2
MW:212.29
EINECS:
Product Categories:Amines and Anilines;Heterocycles
Mol File:141449-85-6.mol
2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE Structure
2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE Chemical Properties
Boiling point 295.4±33.0 °C(Predicted)
density 1.076±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka10.72±0.20(Predicted)
form solid
color White to off-white
Safety Information
HS Code 2933998090
MSDS Information
2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE Usage And Synthesis
Uses2-Boc-Hexahydro-pyrrolo[3,4-C]pyrrole is an organic synthetic intermediate compound used in the preparation of anticancer agent compounds and sigma-2 ligands.
Synthesis
5-Benzyl-2-Boc-hexahydro-pyrrolo[3,4-C]pyrrole

186202-73-3

2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE

141449-85-6

Example 6C: Synthesis of tert-butyl hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate To a solution of tert-butyl 5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (107.8 g, 0.356 mol), the product of Example 6B, in methanol (250 mL) was added wet 20% Pd(OH)2/C catalyst (10.8 g). The reaction mixture was hydrogenated for 2.5 hours at 50°C and 60 psi under a hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to afford the title compound tert-butyl hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (74 g, 0.35 mol, 98% yield). Mass spectrum (DCI/NH3) m/z: 213 ([M+H]+).

References[1] Patent: US2005/65178, 2005, A1. Location in patent: Page/Page column 22
[2] Patent: US2005/101602, 2005, A1. Location in patent: Page/Page column 28
[3] Patent: WO2009/111550, 2009, A1. Location in patent: Page/Page column 37
[4] Patent: WO2013/71697, 2013, A1. Location in patent: Paragraph 00250
[5] Patent: US2014/228361, 2014, A1. Location in patent: Paragraph 0371-0372
Tag:2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE(141449-85-6) Related Product Information
HEXAHYDRO-PYRROLO[3,4-B]PYRROLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER HEXAHYDRO-PYRROLO[3,2-B]PYRROLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Pyrrolo[3,4-b]pyrrole-5(1H)-carboxylic acid, hexahydro-, ethyl ester 2-Boc-6-oxo-2-azaspiro[3.4]octane 2-Boc-5-oxo-octahydro-isoindole hexahydrocyclopenta[c]pyrrol-5(1H)-one N-BOC-HEXAHYDRO-5-OXOCYCLOPENTA[C]PYRROLE (3aR,6aS)-benzyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester (Meso-3aR,5r,6aS)-tert-butyl 5-hydroxyhexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate 2-methyl-octahydrocyclopenta[c]pyrrol-5-one 2-methyl-octahydrocyclopenta[c]pyrrol-5-one (cis)-5-Boc-Hexahydro-pyrrolo[3,4-b]pyrrole,5-Boc-Hexahydro-pyrrolo[3,4-b]pyrrole CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE cis-2-Boc-hexahydropyrrolo[3,4-c]pyrrole 2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE

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