- Boc-L-Dap-OH
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2026-09-11
- CAS:73259-81-1
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T+
- Boc-Dap-OH
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2026-06-30
- CAS:73259-81-1
- Min. Order: 1KG
- Purity: 98.0%
- Supply Ability: 10000KGS
- Boc-Dap-OH
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- $1.00
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2020-01-06
- CAS:73259-81-1
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 100KG
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| | Boc-Dap-OH Basic information |
| Product Name: | Boc-Dap-OH | | Synonyms: | N-Boc-beta-amino-L-alanine;(2S)-3-amino-2-{[(tert-butoxy)carbonyl]amino}propanoic acid;N-alpha-L-(Butoxycarbonyl)-2,3-diaMinopropionic aci;3-Amino-N-(tert-butoxycarbonyl)-L-alanine 97%;3-Amino-Boc-L-alanin;Boc-Dapa-OH;3-AMINO-(TERT-BUTOXYCARBONYL)-L-ALANINE;Nα-Boc-L-2,3-diaminopropionic acid≥ 98% (HPLC) | | CAS: | 73259-81-1 | | MF: | C8H16N2O4 | | MW: | 204.22 | | EINECS: | 1533716-785-6 | | Product Categories: | Amino Acids | | Mol File: | 73259-81-1.mol |  |
| | Boc-Dap-OH Chemical Properties |
| Melting point | 210 °C (dec.) | | alpha | -5.5 º (c=1, acetic acid) | | Boiling point | 364.4±37.0 °C(Predicted) | | density | 1.189±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | solubility | DMSO (Slightly, Heated, Sonicated), Water (Sparingly, Heated, Sonicated) | | form | Solid | | pka | 2.88±0.16(Predicted) | | color | White to Off-White | | Optical Rotation | [α]20/D +5.5±1°, c = 1% in methanol: water (1:1) | | BRN | 4182136 | | Major Application | peptide synthesis | | InChI | InChI=1S/C8H16N2O4/c1-8(2,3)14-7(13)10-5(4-9)6(11)12/h5H,4,9H2,1-3H3,(H,10,13)(H,11,12)/t5-/m0/s1 | | InChIKey | KRJLRVZLNABMAT-YFKPBYRVSA-N | | SMILES | C(O)(=O)[C@H](CN)NC(OC(C)(C)C)=O | | CAS DataBase Reference | 73259-81-1(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | F | 10 | | HazardClass | IRRITANT | | HS Code | 29241990 | | Storage Class | 11 - Combustible Solids |
| | Boc-Dap-OH Usage And Synthesis |
| Chemical Properties | White powder | | Uses | Reactant for:
- Protein assembly directed by synthetic molecular recognition motifs
- Solid phase synthesis of gramicidin S cyclic analogs with antibiotic and hemolytic activities
- Synthesis of HCV protease inhibitor modified analogs
- Solid phase synthesis of peptidic V1a receptor agonists
- Directed peptide assembly at lipid-water interface
| | Uses | (S)-3-amino-2-(tert-Butoxycarbonylamino)propionic acid (Boc-Dap-OH) is a derivative of amino acids, mainly used as an intermediate in organic synthesis and pharmaceutical chemistry, and can be used in the synthesis of peptide drug molecules and bioactive molecules. | | Definition | Boc-Dap-OH is an amino acid molecule that is a zwitterion. Therefore, the addition of a base is required to prepare a nucleophilic amino acid. It is commonly acts as a nucleophile to attack the acyl carbon.
| | Preparation | The raw material was dissolved inabsolute ethanol (5 mL), and the reaction flask was immersed in a water bath at 25 C. To the alcoholicsolution, 10% palladium-carbon (22.9 mg) and 1,4-cyclohexadiene (10 equivalents with respect to4; 0.47 mL, 5.0 mmol) were added, and the mixture was allowed to react under magnetic stirringovernight. After filtration over a short pad of Celite 545, the solvent was evaporated under reducedpressure conditions, and the solid residue was partitioned in a 1:1 (v/v) H2O/EtOAc mixture (10 mL).The aqueous phase was separated, back extracted with EtOAc (3 10 mL), concentrated under reducedpressure conditions, and lyophilized.Finally, the target product Boc-Dap-OH is obtained.
| | reaction suitability | reaction type: Boc solid-phase peptide synthesis |
| | Boc-Dap-OH Preparation Products And Raw materials |
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