S14-95 manufacturers
- Phenylpyropene C
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- $2500.00
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2026-05-11
- CAS:419532-92-6
- Purity:
- Supply Ability: 10g
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| Product Name: | S14-95 | | Synonyms: | S14-95;2H,11H-Naphtho[2,1-b]pyrano[3,4-e]pyran-11-one, 3-(acetyloxy)-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-4,4,6a,12b-tetramethyl-9-phenyl-, (3S,4aR,6aR,12aR,12bS)-;S14-95, JAK/STAT pathway inhibitor | | CAS: | 419532-92-6 | | MF: | C28H34O5 | | MW: | 450.57 | | EINECS: | | | Product Categories: | | | Mol File: | 419532-92-6.mol |  |
| | S14-95 Chemical Properties |
| Boiling point | 559.0±50.0 °C(Predicted) | | density | 1.20±0.1 g/cm3(Predicted) |
| | S14-95 Usage And Synthesis |
| Uses | Phenylpyropene C (S14-95), a JAK/STAT pathway inhibitor, can inhibit IFN-γ mediated expression of the reporter gene (IC50=5.4~10.8 μM). Phenylpyropene C also is an inhibitor of acyl-CoA, with an IC50 of 16.0 μM[1][2]. | | IC 50 | ACAT: 16.0 μM (IC50) | | References | [1] Rho MC, et, al. Phenylpyropene C, a new inhibitor of acyl-CoA: cholesterol acyltransferase produced by Penicillium griseofulvum F1959. J Antibiot (Tokyo). 2002 Feb;55(2):211-4. DOI:10.7164/antibiotics.55.211
[2] Erkel G, et, al. S14-95, a novel inhibitor of the JAK/STAT pathway from a Penicillium species. J Antibiot (Tokyo). 2003 Apr;56(4):337-43. DOI:10.7164/antibiotics.56.337 |
| | S14-95 Preparation Products And Raw materials |
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