2(1H)-Quinolinone, 6-[(2R,5R)-2-methyl-5-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]-1-pyrrolidinyl]-4-(trifluoromethyl)- manufacturers
- LGD-2941
-
- $1970.00
-
2026-08-03
- CAS:847235-85-2
- Purity: 99.90%
- Supply Ability: 10g
|
| | 2(1H)-Quinolinone, 6-[(2R,5R)-2-methyl-5-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]-1-pyrrolidinyl]-4-(trifluoromethyl)- Basic information |
| | 2(1H)-Quinolinone, 6-[(2R,5R)-2-methyl-5-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]-1-pyrrolidinyl]-4-(trifluoromethyl)- Chemical Properties |
| Melting point | 246-248 °C | | Boiling point | 496.8±45.0 °C(Predicted) | | density | 1.422±0.06 g/cm3(Predicted) | | pka | 10.04±0.70(Predicted) |
| | 2(1H)-Quinolinone, 6-[(2R,5R)-2-methyl-5-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]-1-pyrrolidinyl]-4-(trifluoromethyl)- Usage And Synthesis |
| Uses | LGD-2941 is an orally active, potent and selective androgen receptor modulator. LGD-2941 shows excellent anabolic activity in muscle with reduced effect on the prostate in a rat model of hypogonadism. LGD-2941 also improves bone strength in a rat model of post-menopausal osteoporosis[1]. | | References | [1] Martinborough E, et al. Substituted 6-(1-pyrrolidine)quinolin-2(1H)-ones as novel selective androgen receptor modulators. J Med Chem. 2007 Oct 18;50(21):5049-52. DOI:10.1021/jm070231h |
| | 2(1H)-Quinolinone, 6-[(2R,5R)-2-methyl-5-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]-1-pyrrolidinyl]-4-(trifluoromethyl)- Preparation Products And Raw materials |
|