5-Chloro-2-mercaptobenzimidazole

5-Chloro-2-mercaptobenzimidazole Suppliers list

Company Name:	TCI (Shanghai) Development Co., Ltd.
Tel:	021-67121386
Email:	Sales-CN@TCIchemicals.com

Company Name:	Wuhan Chemwish Technology Co., Ltd
Tel:	86-027-67849912
Email:	sales@chemwish.com

5-Chloro-2-mercaptobenzimidazole manufacturers

5-Chloro-2-mercaptobenzimidazole Basic information

Product Name:	5-Chloro-2-mercaptobenzimidazole
Synonyms:	5-chloro-2(3)-benzimidazolethione;5-chloro-2-benzimidazolinethion;6-CHLORO-1H-BENZIMIDAZOLE-2-THIOL;6-CHLORO-1H-BENZO[D]IMIDAZOLE-2-THIOL;5-CHLORO-2-MERCAPTOBENZIMIDAZOLE;5-CHLORO-2-BENZIMIDAZOLETHIOL;5-CHLOROBENZIMIDAZOLE-2-THIOL;AKOS BBS-00000469
CAS:	25369-78-2
MF:	C7H5ClN2S
MW:	184.65
EINECS:	246-903-5
Product Categories:	Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines;BENZIMIDAZOLE
Mol File:	25369-78-2.mol

5-Chloro-2-mercaptobenzimidazole Chemical Properties

Melting point	290-292 °C
Boiling point	300.7±44.0 °C(Predicted)
density	1.4750 (rough estimate)
refractive index	1.6100 (estimate)
storage temp.	Storage temp. 2-8°C
pka	9.71±0.30(Predicted)
form	powder to crystal
color	White to Light yellow to Light orange
Sensitive	Air Sensitive
InChI	1S/C7H5ClN2S/c8-4-1-2-5-6(3-4)10-7(11)9-5/h1-3H,(H2,9,10,11)
InChIKey	ZZIHEYOZBRPWMB-UHFFFAOYSA-N
SMILES	ClC1=CC=C2N([H])C(S[H])=NC2=C1
CAS DataBase Reference	25369-78-2(CAS DataBase Reference)

Safety Information

Hazard Codes	T,Xi
Risk Statements	25-36/37/38-36
Safety Statements	45-28A-36-26
RIDADR	UN2811
WGK Germany	WGK 3
RTECS	DE1605000
HazardClass	6.1
PackingGroup	III
HS Code	29339980
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2
Toxicity	mouse,LD50,intravenous,56mg/kg (56mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04403,

MSDS Information

Provider	Language
ACROS	English
ALFA	English

5-Chloro-2-mercaptobenzimidazole Usage And Synthesis

Chemical Properties	white to yellowish crystalline powder
Uses	Tyrosinase-IN-22 (compound 4) is an inhibitor of tyrosinase substrates (L-tyrosine and L-dopa) with IC50s of 60 nM and 30 nM, respectively. Tyrosinase-IN-22 also shows potent antioxidant and anti-melanogenic properties, thus can be used for relevant researches[1].
References	[1] Yoon D, et al. In vitro and in vivo anti-pigmentation effects of 2-mercaptobenzimidazoles as nanomolar tyrosinase inhibitors on mammalian cells and zebrafish embryos: Preparation of pigment-free zebrafish embryos. Eur J Med Chem. 2024 Feb 15;266:116136. DOI:10.1016/j.ejmech.2024.116136

5-Chloro-2-mercaptobenzimidazole Preparation Products And Raw materials

Preparation Products

Tag:5-Chloro-2-mercaptobenzimidazole(25369-78-2) Related Product Information

Triclabendazole 5-Chloro-2-mercaptobenzimidazole 2-Mercaptobenzimidazole 5,6-Dichlorobenzimidazole-2-thiol 6-Chloro-1H-benzimidazole 5-Chloro-1-isopropyl-1H-benzo[d]imidazole-2-thiol 4,5,6,7-Tetrahydro-5α-methyl-6-(3-methyl-2-butenyl)-8-chloroimidazo[4,5,1-jk][1,4]benzodiazepine-2(1H)-thione 5-chloro-1H-benzimidazole-2-sulfonic acid 5-Chloro-1-(2-methoxyethyl)-1H-benzimidazole-2-thiol [(5-Chloro-1H-benzimidazol-2-yl)sulfanyl]acetic acid Subendazole 1,3-Dihydro-5-chloro-1-methyl-3-phenyl-2H-benzimidazole-2-thione methyl [(5-chloro-1H-benzimidazol-2-yl)sulfanyl]acetate 5-Chloro-6-((1-chloro-2-naphthalenyl)oxy)-2-(methylthio)-1H-benzimidaz ole 6-Chloro-5-fluorobenzimidazole-2-thiol 5,7-Dichloro-1H-benzimidazole-2-thiol 6,7-Dichloro[1,3]thiazolo[3,2-a][1,3]benzimidazol-3(2H)-one 1-Benzyl-5-chloro-1H-benzimidazole-2-thiol