5-Chloro-2-mercaptobenzimidazole manufacturers
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| | 5-Chloro-2-mercaptobenzimidazole Basic information |
| | 5-Chloro-2-mercaptobenzimidazole Chemical Properties |
| Melting point | 290-292 °C | | Boiling point | 300.7±44.0 °C(Predicted) | | density | 1.4750 (rough estimate) | | refractive index | 1.6100 (estimate) | | storage temp. | Storage temp. 2-8°C | | form | powder to crystal | | pka | 9.71±0.30(Predicted) | | color | White to Light yellow to Light orange | | Sensitive | Air Sensitive | | InChI | 1S/C7H5ClN2S/c8-4-1-2-5-6(3-4)10-7(11)9-5/h1-3H,(H2,9,10,11) | | InChIKey | ZZIHEYOZBRPWMB-UHFFFAOYSA-N | | SMILES | ClC1=CC=C2N([H])C(S[H])=NC2=C1 | | CAS DataBase Reference | 25369-78-2(CAS DataBase Reference) |
| Hazard Codes | T,Xi | | Risk Statements | 25-36/37/38-36 | | Safety Statements | 45-28A-36-26 | | RIDADR | UN2811 | | WGK Germany | WGK 3 | | RTECS | DE1605000 | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29339980 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2 | | Toxicity | mouse,LD50,intravenous,56mg/kg (56mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04403, |
| | 5-Chloro-2-mercaptobenzimidazole Usage And Synthesis |
| Chemical Properties | white to yellowish crystalline powder | | Uses | Tyrosinase-IN-22 (compound 4) is an inhibitor of tyrosinase substrates (L-tyrosine and L-dopa) with IC50s of 60 nM and 30 nM, respectively. Tyrosinase-IN-22 also shows potent antioxidant and anti-melanogenic properties, thus can be used for relevant researches[1]. | | References | [1] Yoon D, et al. In vitro and in vivo anti-pigmentation effects of 2-mercaptobenzimidazoles as nanomolar tyrosinase inhibitors on mammalian cells and zebrafish embryos: Preparation of pigment-free zebrafish embryos. Eur J Med Chem. 2024 Feb 15;266:116136. DOI:10.1016/j.ejmech.2024.116136 |
| | 5-Chloro-2-mercaptobenzimidazole Preparation Products And Raw materials |
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