Product Details
| Product Name: PICEATANNOL | CAS No.: 10083-24-6 |
| Min. Order: 1KG | Purity: 99% |
| Supply Ability: g-kg-tons, free sample is available | Release date: 2025/09/25 |
| Lead time: In stock | Packaging: bottle/drum/bucket/IBC, as request. |
| Delivery: By sea, by air, by express | Origin: Manufacturer |
| Name: Sun |
1. Product information
| Name | Piceatannol |
|---|---|
| Synonym | More Synonyms |
| Description | Piceatannol is a selective inhibitor of protein tyrosine kinase Syk. It could inhibit ICa,L, Ito, IKr, Ca2+ transients and Na+-Ca2+ exchange except IK1. Shows multiple biological activities such as anti-inflammatory, antiproliferative and immunomodulatory effects.In vitro: The treatment of human myeloid cells with piceatannol suppressed TNF-induced DNA binding activity of NF-κB. The effect of piceatannol was not restricted to myeloid cells, as TNF-induced NF-κB activation was also suppressed in lymphocyte and epithelial cells. Piceatannol also inhibited NF-κB activated by H2O2, PMA, LPS, okadaic acid, and ceramide. [1] |
|---|---|
| Related Catalog | Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Syk Research Areas >> Cancer Natural Products >> Phenols |
| References | [1]. Kazuhiro Ashikawa et al. Piceatannol Inhibits TNF-Induced NF-κB Activation and NF-κB-Mediated Gene Expression Through Suppression of IκBα Kinase and p65 Phosphorylation. J Immunol, 2002 Dec 1, 169(11):6490-7. [2]. Wen-Pin Chen et al. Piceatannol, a derivative of resveratrol, moderately slows INa inactivation and exerts antiarrhythmic action in ischaemia-reperfused rat hearts. Br J Pharmacol.2009 Jun, 157(3), 381-391. |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 507.3±38.0 °C at 760 mmHg |
| Melting Point | 223-227ºC |
| Molecular Formula | C14H12O4 |
| Molecular Weight | 244.243 |
| Flash Point | 252.2±21.4 °C |
| Exact Mass | 244.073563 |
| PSA | 80.92000 |
| LogP | 2.69 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.801 |
| Storage condition | 2-8°C |
| Water Solubility | H2O: 0.5 mg/mL |
Piceatannol MSDS(Chinese) |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | 24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2907299090 |
| HS Code | 2907299090 |
|---|---|
| Summary | 2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0% |
| A unique mechanism of curcumin inhibition on F1 ATPase Biochem. Biophys. Res. Commun. 452(4) , 940-4, (2014) • Polyphenols lowered the rotation rate of F1 ATPase by increasing catalytic dwell. • Curcumin showed different inhibitory mechanism from other polyphenols. • γ subunit carboxyl terminus is not requir... | |
| Antibody-opsonized bacteria evoke an inflammatory dendritic cell phenotype and polyfunctional Th cells by cross-talk between TLRs and FcRs. J. Immunol. 194(4) , 1856-66, (2015) During secondary immune responses, Ab-opsonized bacteria are efficiently taken up via FcRs by dendritic cells. We now demonstrate that this process induces cross-talk between FcRs and TLRs, which resu... | |
| TH2 cells and their cytokines regulate formation and function of lymphatic vessels. Nat. Commun. 6 , 6196, (2015) Lymphatic vessels (LVs) are critical for immune surveillance and involved in the pathogenesis of diverse diseases. LV density is increased during inflammation; however, little is known about how the r... |
| 3,3',4'5-Tetrahydroxystilbene |
| E-Piceatannol |
| 1,2-Benzenediol, 4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]- |
| 3,3′,4,5′-Tetrahydroxy-trans-stilbene |
| 3,3',4,5'-Tetrahydroxy-trans-stilbene |
| 3,4,3',5'-Tetrahydroxy-trans-stilbene |
| 4-[(E)-2-(3,5-Dihydroxyphenyl)vinyl]benzene-1,2-diol |
| 3,5,3',4'-tetrahydroxystilbene |
| 4-[(E)-2-(3,5-Dihydroxyphenyl)vinyl]-1,2-benzenediol |
| Piceatannol |
| 4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol |
| MFCD00221715 |
| 4-(2-(3,5-Dihydroxyphenyl)vinyl)-1,2-benzenediol |
| (E)-4-[2-(3,5Dihydroxyphenyl)ethenyl]1,2-benzenediol |
| (E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol |
| 5-[(E)-2-(3,4-Dihydroxyphenyl)vinyl]benzene-1,3-diol |
| trans-3,3',4,5'-tetrahydroxystilbene |
| 3,3',4,5'-tetrahydroxystilbene |
| Piceatannol, (E)- |
2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
For more details, pls contact us freely.
Email address : Sun@fdachem.com
Mob: 86 13526505137
WhatsApp/Skype/Wechat/LINE: 86 13526505137
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