Product Details
| Product Name: Sugammadex soidum | CAS No.: 343306-79-6 |
| Min. Order: 1KG | Purity: 99% |
| Supply Ability: 20 Tons | Release date: 2020/11/16 |
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Synonyms: Org25969; Org-25969; Org 25969; 361LPM2T56; Sugammadex; trade name: Bridion. Sugammadex sodium |
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CAS NO : 343306-79-6 |
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Molecular Formula: C72H104Na8O48S8 |
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Molecular Weight: 2177.9742 |
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Purity: 98% |
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Solubility: In DMSO |
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Storage: -20°C |
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Remarks:Sugammadex soidum is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA). Sugammadex is a modified -cyclodextrin, with a lipophilic core and a hydrophilic periphery. This gamma cyclodextrin has been modified from its natural state by placing eight carboxyl thio ether groups at the sixth carbon positions. These extensions extend the cavity size allowing greater encapsulation of the rocuronium molecule. These negatively charged extensions electrostatically bind to the quaternary nitrogen of the target as well as contribute to the aqueous nature of the cyclodextrin. Sugammadex's binding encapsulation of rocuronium is one of the strongest among cyclodextrins and their guest molecules. The rocuronium molecule (a modified steroid) bound within sugammadex's lipophilic core, is rendered unavailable to bind to the acetylcholine receptor at the neuromuscular junction.
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- Since: 2019-10-11
- Address: Room 201, 11 Xinhouying Road, Xicheng Lian, Xinluo District, Longyan City, Fujian Province, China

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