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Postion:Product Catalog >API>Circulatory system drugs>Angina Pectoris Drugs>Diltiazem
Diltiazem
  • Diltiazem
  • Diltiazem
  • Diltiazem

Diltiazem

Price $10 $20
Package 1Kg/Drum 10Kg/Drum
Min. Order: 1Kg/Drum
Supply Ability: 2000 kg
Update Time: 2021-08-31

Product Details

Product Name: Diltiazem CAS No.: 42399-41-7
EC-No.: 255-796-4 Min. Order: 1Kg/Drum
Purity: 99.8% Supply Ability: 2000 kg
Release date: 2021/08/31

Product information
CAS No: 42399-41-7
MF: C22H26N2O4S

Delivery TimeIn one weekPackageFoil bag or drum
Portwuhan/shanghai/guangzhou PortProduction Capacity50000 Kilogram/Month
Purity99% BY HPLCStorageSealed,light and oxygen resistant
Transportationby sea or airLimitNum1 Kilogram
Test MethodUV/HPLCAppearanceWhite crystal powder or liquid
PaymentT/T, Western union , bitcoin,USDTHeavy Metaleppm
Residue on Ignition≤0.1%Related Substances≤0.5%
Valid Period2 years under the proper storedBrand NameMonad
H.S. codeN/A


Used

Diltiazem is a potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. Its pharmacological activity is somewhat similar to verapamil, another nondihydropyridine (non-DHP) calcium channel blocker.Chemically, it is based upon a 1,4-thiazepine ring, making it a benzothiazepine-type calcium channel blocker.
It is a vasodilator of coronary and peripheral vessels, which reduces peripheral resistance and afterload, though not as potent as the dihydropyridine (DHP) calcium channel blockers. This results in minimal reflexive sympathetic changes.
Diltiazem has negative inotropic, chronotropic, and dromotropic effects. This means diltiazem causes a decrease in heart muscle contractility - how strong the beat is, lowering of heart rate - due to slowing of the sinoatrial node, and a slowing of conduction through the atrioventricular node - increasing the time needed for each beat. Each of these effects results in reduced oxygen consumption by the heart, reducing angina symptoms. These effects also reduce blood pressure by causing less blood to be pumped out.

Specification

Product NameDiltiazem
cas no.42399-41-7
Other NameCoras;Adizem XL;TILDIEM300LP;Diltiazem;DILTIAZEN;
Density1.3±0.1 g/cm3
Boiling Point594.4±50.0 °C at 760 mmHg
Molecular FormulaC22H26N2O4S
Molecular Weight414.518
Flash Point313.3±30.1 °C
Exact Mass414.161316
PSA84.38000
LogP3.63
Vapour Pressure0.0±1.7 mmHg at 25°C
Index of Refraction1.621

Article illustration

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Company Profile Introduction

Wuhan Monad Medicine Tech Co.,LTD is a research and development, production, sales in one high-tech company, own about 100 kinds of products, can provide about more than 30000 kinds of products. Mainly involves API, pharmaceutical intermediates and natural extract etc. For many years, the skill with international leading product research and development technology and advanced transnational enterprise management pattern, for global in more than 100 countries nearly 1000 companies continue to offer high quality products and service, and has been with the world 500 strong pharmaceutical and biotechnology company keep the strategic cooperative partnership. The company has a fine chemical and largest chemical production base, with perfect quality assurance system and perfect quality control system; Have many sets of high pressure liquid chromatography,gaschromatographyandultravioletspectrophotometer, the quality of product effective analysis and monitoring. The company has passed ISO9001 quality system certification. With import and export right, have dangerous goods business license, apply for through the three yi-drug purchase and management. All personnel of the company are have bachelor degree or above, majoring in own r&d center, test base and production base, the employee of the company from a senior engineer or engineer titles of senior technical staff and technicians, laboratory assistant, etc better echelon. In the New Year, we will continue to uphold the "honest labor, sincere service, the good faith society, constant innovation," the purpose, with the first-class products and high quality services to meet the market demand, Is dedicated to domestic partners and international well-known enterprise together hand in hand, create a better future.

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  • Since: 2016-11-03
  • Address: 58 Optics Valley Avenue, East Lake New Technology Development Zone, Wuhan, Hubei, China 430000
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