Scopolamine hydrobromide

Product Name: Scopolamine hydrobromide

Synonyms: Benzeneacetic acid, a-(hydroxyMethyl)-, (1a,2b,4b,5a,7b)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-ylester, hydrobroMide (1:1), (aS)-;ScopolaMine HBr Trihydrate;ScopolaMine-d3 HBr 3H2O;Hyosol;Tranaxine;Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide (1:1), (αS)-;(1R,2S,4R,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0²;Hyoscine HydrobroMide Trihydrate, (1α,2β,4β,5α,7β)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl Ester HydrobroMide Trihydrate

CAS: 114-49-8

MF: C17H21NO4.BrH

MW: 384.26

EINECS: 204-050-6

Mol File: 114-49-8.mol

Chemical Properties： Off-White Solid

Uses：An acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant

Definition ChEBI: A hydrobromide that is obtained by reaction of scopolamine with hydrogen bromide.

General Description：Scopolamine hydrobromide(hyoscine hydrobromide) occurs as white orcolorless crystals or as a white, granular powder. It is odorlessand tends to effloresce in dry air. It is freely soluble inwater (1:1.5), soluble in alcohol (1:20), only slightly solublein chloroform, and insoluble in ether.

Scopolamine is a competitive blocking agent of theparasympathetic nervous system as is atropine, but it differsmarkedly from atropine in its action on the higher nervecenters. Both drugs readily cross the blood-brain barrierand, even at therapeutic doses, cause confusion, particularlyin the elderly.