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Postion:Product Catalog >API>Antipyretic analgesics>Antipyretic analgesics>Antipyrine
Antipyrine
  • Antipyrine
  • Antipyrine
  • Antipyrine
  • Antipyrine
  • Antipyrine

Antipyrine NEW

Price $1
Package 1g
Min. Order: 1g
Supply Ability: 5ton/month
Update Time: 2025-09-28

Product Details

Product Name: Antipyrine CAS No.: 60-80-0
EC-No.: 246-386-6 Min. Order: 1g
Purity: 99% Supply Ability: 5ton/month
Release date: 2025/09/28

Antipyrine (also known as phenazone) is a synthetic pyrazolone derivative with the following key characteristics:

Historical Use: Developed in the 1880s, it was one of the first widely used synthetic analgesics (pain relievers) and antipyretics (fever reducers).

Mechanism: Acts as a mild non-opioid analgesic and antipyretic, though its exact mechanism is less defined than modern NSAIDs (e.g., it weakly inhibits prostaglandin synthesis).

Current Status: Largely obsolete for systemic use (oral/parenteral) due to:

    • Risk of Agranulocytosis: A potentially life-threatening drop in white blood cells.

    • Skin Reactions: Risk of rashes and hypersensitivity.

    • Availability of Safer Alternatives: Like paracetamol (acetaminophen) and ibuprofen.

      Modern Applications:

    • Otology: A common active ingredient in ear drops (e.g., Auralgan) combined with benzocaine. It reduces inflammation and pain associated with otitis media/externa.

    • Research: Used as a marker compound to measure cytochrome P450 enzyme activity in drug metabolism studies (the "antipyrine test").

      Chemistry: White crystalline powder (C₁₁H₁₂N₂O), structurally related to aminophenazone (aminopyrine) and metamizole.

In short: Antipyrine is a historical analgesic/antipyretic now primarily used topically in ear drops for earache and as a research tool in pharmacology. Its systemic use is discontinued due to safety concerns.

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Company Profile Introduction

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber. Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement. We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves. Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.

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  • Since: 2006-04-03
  • Address: Room 2015, No.2 Building Kaixin Mansion, No.107 Jinqiao Ave, Wuhan, China
INQUIRY
Betty Shu
+8613986145403
info@fortunachem.com