Amlodipine Besylate

Amlodipine besylate, also known as luohuoxi and anlodipine, is a common drug in the clinical treatment of hypertension and angina pectoris in China. It is a calcium channel blocker. It can directly relax vascular smooth muscle cells by blocking calcium ions to enter myocardial and vascular smooth muscle cells, In clinic, it is used alone or combined with other antihypertensive drugs to treat essential hypertension. The mechanism of action in the treatment of chronic stable angina pectoris and variant angina pectoris has not been fully determined, but it can relieve angina pectoris by dilating peripheral small arteries and coronary arteries, reducing total peripheral vascular resistance, relieving coronary artery spasm, reducing cardiac afterload, reducing cardiac energy consumption and oxygen demand.