Cimetidine NEW

Cimetidine Cas 51481-61-9

Specification

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Cimetidine is a medication that belongs to a class of drugs called H2 (histamine-2) receptor blockers. It was one of the first widely successful drugs of its kind, marketed under the brand name Tagamet.

How It Works

Its primary function is to reduce the production of stomach acid. It achieves this by blocking histamine from stimulating the acid-producing cells (parietal cells) in the stomach lining. Less acid means:

• Relief from heartburn (acid reflux)

• Healing of stomach and duodenal ulcers

• Reduction of symptoms in conditions like GERD (Gastroesophageal Reflux Disease)

Common Uses

Cimetidine was historically prescribed to treat:

• Peptic ulcers (both gastric and duodenal)

• GERD

• Conditions where reducing stomach acid is beneficial (e.g., Zollinger-Ellison syndrome)

Important Considerations

• "The Prototype": Cimetidine was a groundbreaking drug, but it has largely been replaced by newer H2 blockers (like famotidine/Pepcid) and Proton Pump Inhibitors (PPIs like omeprazole/Prilosec), which are often more effective and have fewer side effects.

• Key Side Effect: It is known for a higher likelihood of drug interactions because it inhibits liver enzymes (cytochrome P450) responsible for metabolizing many other common medications (e.g., blood thinners, some antidepressants). This can lead to increased levels of those drugs in the body.

• Other Potential Effects: It has anti-androgen effects and, with long-term high-dose use, was sometimes associated with gynecomastia (enlarged breast tissue in men) and impotence.

In summary, cimetidine is a pioneering stomach acid-reducing medication that is now used less frequently due to newer drugs with better safety profiles and fewer interactions.

Packages

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Payment term

* Wire Transfer/Telegraphic Transfer

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* L/C

Contact information

Spring Zhang

Email: export@fortunachem.com  

Skype: Fortunachem201304       

Wechat/Whatsapp: 18007136271

Tel:   +86-27-59207892

Website: www.fortunachem.com