Product Details
| Product Name: Calcipotriol Monohydrate | CAS No.: 147657-22-5 |
| EC-No.: 689-035-6 | Min. Order: 1g |
| Purity: 97.5% | Supply Ability: 50g |
| Release date: 2026/01/20 | |
| Type: SZ01 |
Calcipotriol Monohydrate Cas 147657-22-5
Specification
Items |
Specification |
Result |
Appearance | White powder | White powder |
Purity | ≥97.5% | 99.10% |
Water | ≤5.0% | 2.2% |
Welcome to contact with us to get more information.
Calcipotriol Monohydrate is a synthetic analog of vitamin D₃ (cholecalciferol) engineered to retain therapeutic potency while minimizing the hypercalcemic side effects of natural vitamin D. Chemically, it differs from endogenous vitamin D₃ by a hydroxyl group at the 24-position and a double bond in the side chain, optimizing its affinity for vitamin D receptors (VDRs) in skin cells.
Mechanistically, it exerts anti-psoriatic effects by binding to VDRs in keratinocytes and immune cells: it inhibits abnormal keratinocyte proliferation, promotes normal differentiation (restoring skin barrier function), and suppresses pro-inflammatory cytokines (e.g., TNF-α, IL-6) and immune cell infiltration—addressing the core pathogenic features of psoriasis.
Clinically, it is a first-line topical therapy for mild-to-moderate plaque psoriasis, available as ointments, creams, gels, or foams for targeted application to lesions (scalp, body). It is often combined with topical corticosteroids (e.g., betamethasone) to enhance efficacy and reduce irritation. Beyond psoriasis, it is being investigated for other hyperproliferative skin conditions (e.g., vitiligo, ichthyosis) due to its regulatory effects on skin cell turnover.
Formulation-wise, it requires stability considerations (protected from light/heat) and is formulated for low systemic absorption, ensuring safety for long-term use. Its role in dermatology underscores its value as a targeted, patient-friendly alternative to systemic therapies for chronic skin disorders.
Packages

Delivery

Payment term
* Wire Transfer/Telegraphic Transfer
* Western Union
* MoneyGram
* L/C
Contact information
Spring Zhang
Email: export@fortunachem.com
Skype: Fortunachem201304
QQ:3169620873
Tel: +86-27-59207892
Website: www.fortunachem.com
Company Profile Introduction
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.
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- Since: 2006-04-03
- Address: Room 2015, No.2 Building Kaixin Mansion, No.107 Jinqiao Ave, Wuhan, China
INQUIRY
Betty Shu
+8613986145403
info@fortunachem.com
+8613986145403
info@fortunachem.com

China