Dimenhydrinate NEW

Dimenhydrinate Cas 523-87-5

Specification

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Dimenhydrinate is an over-the-counter (OTC) medication primarily used to prevent and treat nausea, vomiting, dizziness, and motion sickness.

What It Is

• Class: It belongs to a class of drugs known as antihistamines (specifically an ethanolamine derivative).

  Composition: It is actually a combination of two drugs:

1. Diphenhydramine: An antihistamine (the same active ingredient in Benadryl®).

2. 8-Chlorotheophylline: A mild stimulant similar to caffeine, added to counteract some of the drowsiness caused by diphenhydramine.

Primary Uses (FDA-Approved)

1. Motion Sickness: The most common use. It is effective for preventing and treating symptoms of motion sickness (like seasickness, car sickness, air sickness) including:

• Nausea

  Vomiting

  Dizziness

  Vertigo (spinning sensation)

2. Vertigo: It can help manage dizziness and vertigo caused by inner ear problems (like labyrinthitis or vestibular neuritis).

Common Off-Label & Secondary Uses

• Nausea and Vomiting from General Causes: Sometimes used for nausea from other causes (e.g., viruses, migraines, recovery from surgery), though other prescription medications are often more effective for severe or specific types of nausea.

  Insomnia (Sleep Aid): Due to its strong sedative side effect (from the diphenhydramine component), it is sometimes used as a sleep aid. However, plain diphenhydramine (like in ZzzQuil® or generic sleep aids) is more commonly marketed for this purpose.

  Allergy Relief: Its antihistamine properties can provide minor relief from allergy symptoms (like runny nose, itchy eyes), but it is not typically a first-choice due to its strong sedative effects.

Important Considerations & Warnings

• Drowsiness (Sedation): This is the most significant side effect. It can severely impair your ability to drive or operate machinery. Do not mix with alcohol or other sedatives.

  Timing: For motion sickness prevention, it is most effective when taken 30 minutes to 1 hour before travel.

  Forms: Available as tablets, chewable tablets, liquid, and even injectable forms (the latter by healthcare professionals).

  Anticholinergic Effects: Can cause dry mouth, blurred vision, constipation, and difficulty urinating, especially in older adults.

  Not for Young Children: Should not be used in children under 2 years of age without a doctor's advice due to risk of serious side effects.

  Interactions: Can interact with many medications, including other antihistamines, antidepressants, anxiety medications, and certain bladder control medicines. Always consult a pharmacist or doctor.

  Pregnancy & Breastfeeding: Consult a doctor before use.

Common Brand Names

• Dramamine® (the most famous brand)

  Generic/store brands are widely available as "Dimenhydrinate" or "Motion Sickness Relief."

Alternatives

For motion sickness, other options include:

• Meclizine (Bonine®, Dramamine® Less Drowsy): Often causes less drowsiness.

  Scopolamine (Transderm Scop®): A prescription patch.

  Non-sedating antihistamines like cetirizine or loratadine are not effective for motion sickness.

In summary, Dimenhydrinate is a widely accessible, effective antihistamine mainly used for preventing and treating motion sickness and vertigo, but its strong sedative effects require cautious use.

Disclaimer: This information is for educational purposes only. Always read the drug label and consult with a healthcare professional (doctor or pharmacist) before taking any new medication to ensure it is safe and appropriate for your specific situation.

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Contact information

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