Donepezil

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Donepezil
Synonyms:2-[(1-Benzyl-4-Piperidyl)Methyl]-5,6-Dimethoxy-2,3-Dihydroinden-1-One;1-Benzyl-4-[(5,6-Dimethoxy-1-Indanon-2-Yl) Methyl] Piperidine;2,3-Dihydro-5,6-Dimethoxy-2-((1-(Phenylmethyl)-4-Piperidinyl)Methyl)-1h-Inde;n-1-One;n-Benzyl-4-[(5,6-Dimethoxy-1-Indanon-2-Yl)Methyl] Piperidine;5,6-Dimethoxy-2,3-Dihydro-1h-Inden-1-One
CAS: 120014-06-4
MF:C24H29NO3
MW:379.49
Melting point:207°C
Water Solubility:2.931 mg/L

What is Donepezil

Donepezil is a centrally acting reversible acetylcholinesterase inhibitor. Its main therapeutic use is in the palliative treatment of Alzheimer's disease. Common side effects include gastrointestinal upset. It has an oral bioavailability of 100% and easily crosses the blood-brain barrier. Because it has a biological half-life of about 70 hours, it can be taken once a day.


Donepezil Application:

Donepezil is used to treat confusion (dementia) related to Alzheimer's disease. It does not cure Alzheimer's disease, but it may improve memory, awareness, and the ability to function. This medication is an enzyme blocker that works by restoring the balance of natural substances (neurotransmitters) in the brain.