Tetracaine hydrochloride

Tetracaine hydrochloride (Hydrochloride) is a compound, molecular formula is C15H24N2O2·HCl, molecular weight is 264.36326, white powder, soluble in water, dissolved in ethanol, melting point is 147 ~ 150℃, flash point is 189.3.

Used as a local anesthetic. [1-2]

Chinese name Tetracaine hydrochloride foreign name Tetracaine hydrochloride not name pantocaine; 4-(butamino-benzoic acid-2 -(dimethylamino) ethyl ester hydrochloride Chemical formula C15H24N2O2·HCl Molecular weight 264.36326 CAS Accession No. 136-47-0 EINECS Accession No. 205-248-5 Boiling point 389.4°C at 760 mmHg Soluble in water, soluble in ethanol. External white crystalline powder flash point 189.3 ℃ Local anesthetized hazard symbol R25, R36, R43 steam pressure 2.87E-06mmHg at 25°C local anesthetized surface dosage, 1% solution spray or smear injection means that high dose can cause conduction system inhibition

Product use

[Purpose 1]

Local anesthetic.

【 Purpose 2 】

Local anesthesia is stronger than procaine and more toxic. It can penetrate mucous membrane and is mainly used for mucous membrane anesthesia.

Pharmaceutical analysis

Method name:

Determination of tetracaine hydrochloride - neutralization titration method

Application scope:

The content of tetracaine hydrochloride was determined by titration.

This method is suitable for tetracaine hydrochloride.

Method principle:

After adding glacial acetic acid and acetic anhydride test solution, the samples were heated and reflux for 2 hours, then cooled. After adding mercury acetate test solution and crystal violet indicator solution, the solution was titrated with perchloric acid titrant (0.1mol/L) until the solution showed blue color. The usage of perchloric acid titrant was recorded and calculated.