20-HETE NEW
| Price | $1198 | $2450 |
| Package | 1mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-08 |
Product Details
| Product Name: 20-HETE | CAS No.: 79551-86-3 |
| Purity: 99.79% | Supply Ability: 10g |
| Release date: 2025/11/08 |
Product Introduction
Bioactivity
| Name | 20-HETE |
| Description | 20-HETE promotes cell proliferation and migration in cancer and can be used to study prostate tumors and cardiac hypertrophy by activating the protein kinase C pathway to increase FBXO10 expression.20-HETE promotes cell proliferation and migration in cancer and can be used to study prostate tumors and cardiac hypertrophy by activating the protein kinase C pathway. |
| In vitro | 17-ODYA (1 μM) increased the activity of large-conductance Ca(2+)-activated K+ channels, and this effect was reversed by 20-HETE (10 nM). 20-HETE (1-1000 nM) reduced the diameter of isolated perfused small renal arteries in rats by approximately 15%, and TEA (1 mM) blocked the vasoconstrictor response to 20-HETE (100 nM)[1]. |
| In vivo | 20-HETE contributes to DHT-induced vascular remodeling, independent of blood pressure elevation[2]. |
| Storage | store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 2 mg/mL (6.24 mM), Sonication is recommended. Ethanol : 5 mg/mL (15.6 mM), Sonication is recommended. |
| Keywords | PKC | Human Endogenous Metabolite | 20-HETE | 20HETE | 20 HETE |
| Inhibitors Related | Ellagic acid | Darovasertib | α-Vitamin E | Ro-3306 | Piceatannol | Staurosporine | Methyl-Hesperidin | Mitoxantrone | Fasudil hydrochloride | N-Desmethyltamoxifen hydrochloride | Mitoxantrone dihydrochloride | R59949 |
| Related Compound Libraries | Membrane Protein-targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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