4-Hydroxybenzhydrazide

Name: 4-Hydroxybenzhydrazide

CAS: 5351-23-5

EINECS: 226-326-5

MF: C₇H₈N₂O₂

MW: 152.15

MP: 264–266 °C (dec.) (lit.)

BP: Approx. 370 °C at 760 mmHg (Predicted)

Density: 1.318 g/cm³

Appearance: White to slightly beige fine crystalline powder

Purity: 98% min (HPLC / titration)

Package: 25g, 100g, 500g, 1kg, bulk package (25kg drums / bags)

Application: Versatile hydrazide building block for organic synthesis — condenses with aldehydes / ketones to form hydrazones, reacts with acyl chlorides / carboxylic acids to form diacylhydrazides; pharmaceutical intermediate for antitubercular, antitumor and antiviral agents; ligand for transition metal coordination complexes (hydrazide N/O and phenol O as donor sites); analytical reagent for derivatization and detection of aldehydes / ketones; intermediate for polymers, liquid crystals and functional materials; enzyme inhibitor scaffold.

Other name: 4-Hydroxybenzoic acid hydrazide; p-Hydroxybenzhydrazide; 4-Hydroxybenzoylhydrazine; 4-Hydroxybenzohydrazide

Storage: Store in a tightly sealed container, in a cool, dry and well-ventilated place at 15–25 °C. Air sensitive — protect from air, moisture and light. Keep away from strong oxidizing agents, strong acids and strong bases. Soluble in water (approx. 26.5 g/L), acetic acid / water (1:1), DMSO and DMF; slightly soluble in ethanol and methanol. pKa: 8.57±0.15 (phenolic OH). λmax: 245 nm (in methanol).

Production & Supply: Stable industrial-scale production with ample stock. Sample orders ship within 1–3 working days after payment; bulk quantities (25kg drums / bags) available upon request.

Company Introduction: ALFA (Zhengzhou, Henan, China) is a professional supplier of fine chemicals, hydrazides and organic synthesis building blocks. We provide quality-tested products, flexible packaging and reliable worldwide delivery. Custom specifications and bulk quotations are welcome.