4-Maleimidobenzoic acid NEW

4-Maleimidobenzoic acid

Modify Date: 2024-01-10 07:06:10

4-Maleimidobenzoic acid structure	Common Name	4-Maleimidobenzoic acid
	CAS Number	17057-04-4	Molecular Weight	217.178
	Density	1.5±0.1 g/cm3	Boiling Point	447.1±28.0 °C at 760 mmHg
	Molecular Formula	C11H7NO4	Melting Point	N/A
	MSDS	N/A	Flash Point	224.2±24.0 °C

Purity		Quantity		Budget		Inquiry

Use of 4-Maleimidobenzoic acid 4-Maleimidobenzoic acid is a protein crosslinker. 4-Maleimidobenzoic acid can be used to synthesis maleimidobenzoyl spacers[1].

• Properties

• Spectrum

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 Names

Name	4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid
Synonym	More Synonyms

 4-Maleimidobenzoic acid Biological Activity

Description	4-Maleimidobenzoic acid is a protein crosslinker. 4-Maleimidobenzoic acid can be used to synthesis maleimidobenzoyl spacers[1].
Related Catalog	Research Areas >> Others
References	[1]. Lau A, et, al. Conjugation of doxorubicin to monoclonal anti-carcinoembryonic antigen antibody via novel thiol-directed cross-linking reagents. Bioorg Med Chem. 1995 Oct;3(10):1299-304.

 Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	447.1±28.0 °C at 760 mmHg
Molecular Formula	C11H7NO4
Molecular Weight	217.178
Flash Point	224.2±24.0 °C
Exact Mass	217.037506
PSA	74.68000
LogP	0.77
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.669

 Safety Information

Hazard Codes	Xi: Irritant;
Risk Phrases	36
Safety Phrases	26
HS Code	2925190090

 Synthetic Route

Previous 1/2 Next

4-[[(E)-3-carbo... CAS#:5432-04-2 ~91% 4-Maleimidobenz... CAS#:17057-04-4

Literature: Koechel; Tarloff; Rankin Journal of Medicinal Chemistry, 1983 , vol. 26, # 1 p. 85 - 90

Maleic anhydride CAS#:108-31-6 4-Aminobenzoic acid CAS#:150-13-0 ~84% 4-Maleimidobenz... CAS#:17057-04-4

Literature: Hulubei, Camelia Revue Roumaine de Chimie, 2008 , vol. 53, # 9 p. 743 - 752

4-Aminobenzoic acid CAS#:150-13-0 Maleic acid CAS#:110-16-7 ~93% 4-Maleimidobenz... CAS#:17057-04-4

Literature: Alagic, Amer; Koprianiuk, Agnieszka; Kluger, Ronald Journal of the American Chemical Society, 2005 , vol. 127, # 22 p. 8036 - 8043

 Precursor & DownStream

Precursor  6	Previous 1/2 Next
CAS#:5432-04-2 4-[[(E)-3-carbo...  CAS#:108-31-6 Maleic anhydride  CAS#:150-13-0 4-Aminobenzoic acid  CAS#:110-16-7 Maleic acid
DownStream  5	Previous 1/2 Next
CAS#:29305-46-2 4-(2,5-dioxopyr...  CAS#:123457-83-0 4-(MALEINIMIDO)...  CAS#:64191-06-6 4-N-MALEIMIDOBE...  CAS#:57-13-6 Urea

 Customs

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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