Chlorpheniramine maleate

High Purity 99% Chlorpheniramine Powder CAS NO 113-92-8

Introduction
1.Name:Chlorphenamine Maleate 
2.Cas No:113-92-8
3.MF:C16H19ClN2.C4H4O4 
4.MW.:390.87 
5.Appearance:white crystalline powder 
6.Other Names: Chlorphenamine hydrogen maleate; 1-p-Chlorophenyl-1-(2-pyridyl)-3-dime

Function

Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an is chemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemia-reperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.

Application:

It is the strongest antihistamine
First, the sedative effect is weak and has certain anticholinergic effect. It is an antihistamine for hydrocarbon. It is characterized by strong anti-histamine, small dosage, less side effects and applicable to children. It is used in allergic diseases, insect bites and allergic reactions. The compatibility with antipyretic analgesics is used to cure colds. Packing specification: 25kg pail.