Product Details
| Product Name: tamoxifen | CAS No.: 10540-29-1 |
| Min. Order: 1g | Purity: 99.9% |
| Supply Ability: 1 ton | Release date: 2021/03/17 |
简介
Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
基本信息
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中文名称
他莫昔芬
英文名称
tamoxifen
中文别名
(Z)-2-[4-(1,2-二苯基-1-丁烯)苯氧基]-N,N-二甲基乙胺; 氮位N-去甲基盐酸三苯氧胺; 它莫西芬;
英文别名
trans-2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine; Tamoxifene; [3H]-Tamoxifen; Tamoxen; Tamoxifen;
查看更多英文别名CAS号
10540-29-1
分子式
C26H29NO
分子量
371.51500
精确质量
371.22500
PSA
12.47000
LOGP
5.99610
物化性质
- 外观与性状：
- 细灰白色结晶粉末
- 密度：
- 1.042 g/cm3
- 熔点：
- 97-98ºC
- 闪点：
- 140ºC
- 折射率：
- 1.582
- 储存条件：
- 2-8ºC
- 蒸汽压：
- 1.85E-09mmHg at 25°C
安全信息
- RTECS号：
- KR5919600
- 安全说明：
- S53-S45
- 危险类别码：
- R45; R60; R61; R64
- WGK Germany：
- 3
- 海关编码：
- 2922199090
- 危险品标志：
- T
- 信号词：
- Danger
- 危险性防范说明：
- P201; P263; P308 + P313
- 危险性描述：
- H350; H360; H362
- 危险标志：
- GHS08
Company Profile Introduction
Welcome to hebei Shuoxi biotechnology co., LTD. Shuoxi is a fast developing pharmaceutical intermediates enterprise located in shijiazhuang, capital of hebei province.
Shuoxi analysis research and development center also provides custom synthesis service.
Hebei Shuoxi biotechnology co., LTD can provide customized synthetic chemicals in different quantities in laboratories, factories and industrial scale.
We have more than 10 years experience in this field.
We can offer competitive price for every customer and guarantee the quality of our products.
3. We pay attention to the needs of each customer and build a good relationship with them.
4. We have long-term business relations with Canada, Mexico, Brazil, UK, Russia, Germany, USA, India, South Africa, Malta, Egypt, Armenia, Australia, Philippines, Belgium, Netherlands, Denmark and other countries.
If you have any other questions for me. Please feel free to contact me.
We only produce and sell products that are legal in China. All products are sold only to laboratory research.
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China- Since: 2016-11-14
- Address: NO.108 ZHONGSHAN ROAD, QIAOXI DISTRICT, ShiJiazhuang CITY, CHINA
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