Erucin NEW
| Price | $40 | $89 | $147 |
| Package | 10mg | 25mg | 50mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-27 |
Product Details
| Product Name: Erucin | CAS No.: 4430-36-8 |
| Purity: 99.97% | Supply Ability: 10g |
| Release date: 2026/07/27 |
Product Introduction
Bioactivity
| Name | Erucin |
| Description | Erucin （1-isothiocyanato-4-methylsulfanylbutane） is a dietary isothiocyanate produced by enzymatic hydrolysis of glucoErucin with potential cancer preventive effects, involved in apoptosis and cell cycle blockade through PARP-1 cleavage, p53 and p21，Cyp450, quinone reductase (QR), glutatione transferase (GST) and other pathways. |
| In vitro | In LPS-stimulated RAW 264.7 macrophages, Erucin (2.5 and 5 μmol/L) inhibited NO and PGE₂ production, suppressed NF-κB activity, and reduced expression of TNF-α, IL-6, IL-1β, iNOS, and COX-2[1]. In SH-SY5Y neuroblastoma cells, Erucin (5 μM) activated the Nrf2 pathway, increased intracellular GSH levels, and protected against 6-OHDA-induced oxidative stress[2]. Erucin (30–100 μM) inhibits proliferation and migration, induces apoptosis, releases H₂S, and reduces ERK1/2 phosphorylation in AsPC-1 pancreatic cancer cells[3]. |
| In vivo | In a TPA-induced mouse ear edema model, Erucin (100 and 300 nmol) significantly reduced swelling and decreased iNOS and COX-2 expression[1]. |
| Storage | Store under nitrogen,Store at low temperature Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Saline : 10 mg/mL (62 mM), Solution. DMSO : 125 mg/mL (775 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (20.46 mM), Sonication is recommended. |
| Inhibitors Related | Stavudine | Aceglutamide | Adenosine | Urea | Tamoxifen | Metronidazole | Formamide | Naringin | Dimethyl phthalate | Alginic acid | Dextran sulfate sodium salt (MW 5000) | Sildenafil citrate |
| Related Compound Libraries | Food Sourced Compound Library | Bioactive Compound Library Plus | Multi-Target Compound Library | Natural Product Library | Natural Product Library for HTS |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36 Washington Street, Wellesley Hill, MA
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