Product Details
| Product Name:
Prodigiosin |
CAS No.:
82-89-3 |
| Purity:
99.99% |
Supply Ability:
10g |
| Release date:
2026/08/30 |
Product Introduction
Bioactivity
| Name | Prodigiosin |
| Description | Prodigiosin is a natural red pigment and secondary metabolite that inhibits the Wnt/β-catenin pathway and exhibits antibacterial, antifungal, antimalarial, anticancer, and immunosuppressive activities. |
| In vitro | Prodigiosin treatment (25–500 nM; 24 hours) reduced viability and induced apoptosis in breast cancer cell lines MDA-MB-231 and MDA-MB-468, while decreasing levels of phosphorylated LRP6 and DVL2, active β-catenin, and total β-catenin. Prodigiosin significantly inhibits phosphorylation of GSK3β at Ser9 in HEK293T cells [1].
Prodigiosin inhibits the growth of chytrid fungi Batrachochytrium dendrobatidis and B. salamandrivorans with MIC values of 10 μM and 50 μM, respectively[2]. |
| In vivo | Prodigiosin (5 mg/kg; intraperitoneal injection; twice weekly; for 3 weeks) significantly inhibited tumor growth, reduced tumor cell density, and decreased expression of the proliferation marker Ki-67 [1]. |
| Storage | Store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 20 mg/mL (61.84 mM), Sonication is recommended.
|
| Keywords | Prodigiosin | Fungal |
| Inhibitors Related | Neomycin sulfate | Calcium Propionate | Urea | Kanamycin sulfate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Benzyl propionate | Metronidazole | Doxycycline | Penicillin G sodium salt | Ethyl linoleate | Ethyl acetoacetate |
| Related Compound Libraries | Bioactive Compounds Library Max | Bioactive Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
| Product name |
Price |
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Suppliers |
Update time |
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States