A-Fluralaner CAS 1207041-44-3 98% HPLC Purity Veterinary API | China | Manufacturer

Price	$1
Package	1kg

Product Details

Product Name: A-Fluralaner	CAS No.: 1215216-63-9
Min. Order: 1kg	Purity: 99%
Supply Ability: 10000	Release date: 2025/10/13

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A-Fluralaner (CAS 1215216-63-9) – Chemical Properties & Introduction

Category Description

IUPAC Name：4-[5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]-1-naphthalenecarboxamide

Molecular Formula:C₂₉H₁₄Cl₂F₆N₃O₃

Molecular Weight:640.34 g/mol

CAS Number:1207041-44-3

Appearance:White to pale yellow crystalline powder

Solubility:Insoluble in water; soluble in DMSO, ethanol, and acetone

Melting Point:150–155°C

Chemical Class:Isoxazoline derivative

Mechanism of Action:GABA/glutamate-gated chloride channel inhibitor (arthropod-specific)

Primary Use:Veterinary ectoparasiticide (fleas, ticks, mites)

Target Animals:Dogs and cats (oral or topical administration)

Regulatory Approvals:FDA (USA), EMA (EU), VICH guidelines

Key Benefits:Long-lasting protection (up to 12 weeks), broad-spectrum efficacy, low mammalian toxicity

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Parameter	Specification	Test Method	Acceptance Criteria
1. Physical Properties
Appearance	White to pale yellow crystalline powder	Visual inspection	Complies with reference standard
Solubility	Insoluble in water; Soluble in DMSO, ethanol	Solubility test (USP)	Clear solution at 10 mg/mL
2. Chemical Identification
HPLC Retention Time	Matches reference standard (±5%)	Reverse-phase HPLC (C18 column)	RT 8.2±0.5 minutes
IR Spectrum	Consistent with reference	FT-IR spectroscopy	Major peaks matched
3. Purity & Impurities
Assay (HPLC)	≥ 98.0%	HPLC (UV 254 nm)	98.0-102.0%
Total Impurities	≤ 2.0%	HPLC area normalization	NMT 2.0%
Any Single Impurity	≤ 0.5%	HPLC	NMT 0.5%
4. Residual Content
Water Content	≤ 0.5% w/w	Karl Fischer titration	NMT 0.5%
Residual Solvents	MeOH < 3000 ppm; DMSO < 500 ppm	GC-FID	ICH Q3C Class 2 limits
Heavy Metals	≤ 10 ppm (as Pb)	ICP-MS	USP <231>
5. Microbial Control
Total Aerobic Count	≤ 1000 CFU/g	USP <61>	Complies
Yeast/Mold	≤ 100 CFU/g	USP <61>	Complies
Pathogens	Negative	USP <62>	Absent
6. Packaging & Storage
Packaging	Double PE bag + aluminum foil drum	Visual	Sealed, moisture-proof
Storage Conditions	2-8°C, protected from light	Label verification	Controlled environment

Company Profile Introduction

Wuhan Hao Rong Biotechnology Co., Ltd., located in East Lake high tech Development Zone, Wuhan, is a company specializing in the production and operation of chemical raw materials, flavors and fragrances, food additives, agrochemicals and other products. The company has first-class production equipment, advanced production technology, scientific management system, perfect detection means, and an excellent R & D team. The R & D center of the company has a technical team specialized in research and development, as well as a number of advanced detection, experiment and pilot equipment, and has established a good technical support relationship with a number of scientific research institutions, with strong technical force. The company has a wide range of products, in line with the quality of survival, service and development, customer-centric, integrity management philosophy, do our best to provide customers with quality and cheap raw materials. In addition, haorong also helps customers develop and implement customized system solutions. In these core areas of the chemical industry, haorong's core expertise covers chemicals and application technology, flexible asset management and customized services.

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Wuhan Haorong Biotechnology Co.,ltd