AD 0261 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: AD 0261 | CAS No.: 145600-69-7 |
| Supply Ability: 10g | Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | AD 0261 |
| Description | AD 0261 is a radical scavenger. It has a strong inhibitory action on the generation of lipid peroxides and superoxide anions. |
| Cell Research | For measurement of [3H]TdR incorporation, cells are incubated for 16 h, and additional (6 h) incubation is carried out in the presence of [3H]TdR (0.5 μCi/well). [3H]TdR incorporation is evaluated in a liquid scintillation counter. IL-2 release from lymphocytes is estimated after 20 h incubation by enzyme immunoassay using the commercially available kits. IL-2 receptor expression is quantitated by flow cytometry using a FITC-labelled monoclonal antibody which recognizes a chain of the IL-2 receptor complex. Cell viability is determined by either the trypan blue exclusion test or propidium iodide staining. |
| In vitro | AD 0261 exhibits potent inhibitory activity on lipid peroxide generation (IC50: 0.022 μM) and superoxide anion production (IC50: 0.9-4.0 μM). It dose-dependently inhibits cytokine release/production from PHA-P-stimulated lymphocytes and all lymphocyte activation parameters, achieving 50% inhibition within 1-10 μM. AD 0261 also suppresses ornithine decarboxylase activity (IC50: ~1.0 μM). |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | AD0261 | AD-0261 | AD 0261 |
| Inhibitors Related | Ethoxyquin | Cysteamine hydrochloride | Acetylcysteine | Imeglimin hydrochloride | L-Ascorbic acid | Hesperidin | Glucosamine | Gallic Acid Monohydrate | L-Cystine | Coenzyme Q10 | L-Ascorbic acid sodium salt | Sodium 2-oxopropanoate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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United States