Adenosine 5'-diphosphoribose sodium NEW
| Price | $35 | $54 | $97 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-15 |
Product Details
| Product Name: Adenosine 5'-diphosphoribose sodium | CAS No.: 68414-18-6 |
| Purity: 99.38% | Supply Ability: 10g |
| Release date: 2025/05/15 |
Product Introduction
Bioactivity
| Name | Adenosine 5'-diphosphoribose sodium |
| Description | Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) is a metabolite of nicotinamide adenine nucleotide (NAD+), which is widely present in organisms.Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) is a potent intracellular Ca2+-permeable cation TRPM2 channel activator. Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) is a potent intracellular Ca2+ permeable cation TRPM2 channel activator that also induces autophagy.) |
| In vitro | In mouse embryonic fibroblasts (MEFs), H2O2 treatment demonstrates that the activation of PARP-1 produced Adenosine 5'-diphosphoribose (ADP ribose), which is an activating signal for TRPM2 channels, thereby promoting Ca2+ elevation through extracellular Ca2+ influx and (or) lysosomal Ca2+ release. This process eventually activates early or late autophagy in response to different degrees of oxidative stress.[1] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 20 mg/mL (34.41 mM), Sonication is recommended. H2O : 100 mg/mL (172.03 mM), Sonication is recommended. |
| Keywords | TRPVChannel | TRPV Channel | TRPM2 | TRPChannel | TRP Channel | EndogenousMetabolite | Endogenous Metabolite | Autophagy |
| Inhibitors Related | Sucrose | Stavudine | Hydroxychloroquine | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Paeonol | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid |
| Related Compound Libraries | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Natural Product Library | Drug Repurposing Compound Library | Saccharide and Glycoside Natural Product Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Ion Channel Targeted Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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