Welcome to chemicalbook!
Chinese English Japanese Germany Korea
+1 (818) 612-2111
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structure Search
RFQ
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook Sign in

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >all-trans-4-Oxoretinoic acid
all-trans-4-Oxoretinoic acid
  • all-trans-4-Oxoretinoic acid

all-trans-4-Oxoretinoic acid NEW

Price $6 $4 $2
Package 1kg 10kg 100kg
Min. Order: 1kg
Supply Ability: 100kg
Update Time: 2025-10-13
webchat

Product Details

Product Name: all-trans-4-Oxoretinoic acid CAS No.: 38030-57-8
Min. Order: 1kg Purity: 99%
Supply Ability: 100kg Release date: 2025/10/13
Lead time: in stock Packaging: bag/bottle/drum//IBC, as request
Delivery: By sea, by air, by express Origin: Manufacturer, advantage products
COA, MSDS: Available, contact us for details Contact: Tina

PRODUCT INFORMATION

Common Nameall-trans-4-Oxoretinoic acid
CAS Number38030-57-8Molecular Weight314.41900
Density1.07g/cm3Boiling Point509.9ºC at 760 mmHg
Molecular FormulaC20H26O3Melting Point175-178°C 
MSDSN/AFlash Point276.3ºC
PurityQuantityBudgetInquiry

 Use of all-trans-4-Oxoretinoic acid


all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs).

 Names

Nameall-trans-4-oxoretinoic acid
SynonymMore Synonyms

 all-trans-4-Oxoretinoic acid Biological Activity

Descriptionall-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs).
Related Catalog
Natural Products >> Others
Research Areas >> Metabolic Disease
Target

Human Endogenous Metabolite

In Vitroall-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs)[1]. all-trans-4-Oxoretinoic acid is a biologically active geometric isomer of retinoic acid (RA) [2].
References

[1]. Topletz AR, et al. Induction of CYP26A1 by metabolites of retinoic acid: evidence that CYP26A1 is an important enzyme in the elimination of active retinoids. Mol Pharmacol. 2015;87(3):430-41.

[2]. Stahl W, et al. 4-oxo-retinoic acid is generated from its precursor canthaxanthin and enhances gap junctional communication in 10T1/2 cells. Adv Exp Med Biol. 1996;387:121-8.

 Chemical & Physical Properties

Density1.07g/cm3
Boiling Point509.9ºC at 760 mmHg
Melting Point175-178°C 
Molecular FormulaC20H26O3
Molecular Weight314.41900
Flash Point276.3ºC
Exact Mass314.18800
PSA54.37000
LogP4.78160
Index of Refraction1.565
Storage condition2-8℃

 Toxicological Information

CHEMICAL IDENTIFICATION

  • RTECS NUMBER :

  • VH6599800

  • CHEMICAL NAME :

  • Retinoic acid, 4-oxo-

  • CAS REGISTRY NUMBER :

  • 38030-57-8

  • LAST UPDATED :

  • 199007

  • DATA ITEMS CITED :

  • 5

  • MOLECULAR FORMULA :

  • C20-H26-O3

  • MOLECULAR WEIGHT :

  • 314.46

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Oral

  • DOSE :

  • 100 mg/kg

  • SEX/DURATION :

  • female 11 day(s) after conception

  • TOXIC EFFECTS :

  • Reproductive - Specific Developmental Abnormalities - musculoskeletal system

  • REFERENCE :

  • TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 35,33A,1987

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Oral

  • DOSE :

  • 10 mg/kg

  • SEX/DURATION :

  • female 11 day(s) after conception

  • TOXIC EFFECTS :

  • Reproductive - Specific Developmental Abnormalities - musculoskeletal system

  • REFERENCE :

  • TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 100,162,1989

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Oral

  • DOSE :

  • 20 mg/kg

  • SEX/DURATION :

  • female 8 day(s) after conception

  • TOXIC EFFECTS :

  • Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

  • REFERENCE :

  • TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 95,122,1988

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Oral

  • DOSE :

  • 39 mg/kg

  • SEX/DURATION :

  • female 8 day(s) after conception

  • TOXIC EFFECTS :

  • Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

  • REFERENCE :

  • TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 95,122,1988

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Oral

  • DOSE :

  • 4900 ug/kg

  • SEX/DURATION :

  • female 8 day(s) after conception

  • TOXIC EFFECTS :

  • Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

  • REFERENCE :

  • TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 95,122,1988

 Synthetic Route

Previous 1/3 Next
Article illustration

4-Keto 13-cis-R...

CAS#:71748-57-7

~87%

Article illustration

all-trans-4-Oxo...

CAS#:38030-57-8

Literature: Mironova; Leont'eva; Shevyakov; Alexeeva; Shvets; Demina; Krasnokutskaya; Finkel'shtein; Khodonov Russian Journal of Bioorganic Chemistry, 2002 , vol. 28, # 6 p. 487 - 493
Article illustration

4-Hydroxyretino...

CAS#:38030-59-0

~%

Article illustration

all-trans-4-Oxo...

CAS#:38030-57-8

Literature: Rosenberger Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1698 - 1701
Article illustration

ethyl (2E,4E,6E...

CAS#:81121-19-9

~%

Article illustration

all-trans-4-Oxo...

CAS#:38030-57-8

Literature: Rosenberger Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1698 - 1701

 Precursor & DownStream

Precursor  9

Previous 1/3 Next

  • Article illustration CAS#:71748-57-7
    4-Keto 13-cis-R...

  • Article illustration CAS#:38030-59-0
    4-Hydroxyretino...

  • Article illustration CAS#:81121-19-9
    ethyl (2E,4E,6E...

  • Article illustration CAS#:72526-76-2
    ethyl (2E,6E,8E...

DownStream  1


  • Article illustration CAS#:66592-72-1
    4-Hydroxyretino...

 Synonyms

4-keto-Retinoic Acid
4-oxo-all-rans-retinoic acid
4-Oxoretinoic Acid
all-trans-4-Oxoretinoic Acid
4-oxo-all-trans-retinoic acid
all-trans 4-Keto Retinoic Acid
4-oxo-Retinoic acid
4-Ketoretinoic Acid
4-Oxo-atRA
4-Oxotretinoin



Company Profile

Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. The company integrates research and development, production, customized synthesis, and sales, and is committed to providing customers with high-quality chemical product solutions.


Our Company

Article illustrationArticle illustration


Our Advantage

Rich experience

Our products have been exported to many countries, including Germany, Spain, the United Kingdom, the United States, Australia, the Middle East, Asia, and more. We have received highly positive feedback from our clients and have established long-term friendly cooperative relationships with them.

Excellent quality, purity, and competitive price

Excellent quality is one of the cornerstones of our success. We welcome ordering samples for quality testing.

Article illustration

Safe and fast delivery

We will arrange shipment of spot products as soon as we receive payment.

Customized products are determined based on the synthesis time of different products.

 

Excellent pre-sales and after-sales service

Pre sales:

We are committed to providing the most favorable quotes and detailed information about our products and company.

after-sale service:

We assist buyers in customs clearance by providing necessary documents and information.

If there is any dispute over product quality, we are committed to providing the best solution.

 

• Packaging: 

1kg/bag, 25kg/drum, 50kg/drum, 180kg/drum, 200kg/drum, 1T/bag/drum, standard export packaging or packaging required by customers


Article illustrationArticle illustration

• Shipping

Article illustration

• Delivery:

Within 7 days after receiving your payment


Contact information

For more details, pls contact us freely.

Contact name: Tina

Email address: Tina@fdachem.com

Mob: 86 13213167925

WhatsApp/Skype/Wechat/LINE: 86 15225627621




Company Profile Introduction

Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. The company integrates research and development, production, customized synthesis, and sales, and is committed to providing customers with high-quality chemical product solutions. With our agile custom synthesis capabilities and responsive supply chain system, our products have gained widespread adoption across Asian markets including Japan, South Korea, Singapore, and Malaysia, while also expanding deeply into Europe and the Americas. We have forged long-term strategic partnerships with numerous leading global enterprises in the sector. "Driving value through technology and earning trust through service" is our core mission. Looking ahead, we will continue to focus on technological breakthroughs and green innovation in new materials, collaborating with partners to build a high-quality industrial ecosystem and provide globally competitive solutions with greater foresight.

You may like

Recommended supplier

Product name Price   Suppliers Update time
all-trans-Retinol
 $100.00/5kg
VIP2Y
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
 2024-08-14
ALL-TRANS-RETINAL
 $/
VIP5Y
RongNa Biotechnology Co.,Ltd
 2025-04-29
all-trans-retinoic acid
 $900.00/1T
VIP6Y
Sichuan Zhuoyu Yantang Technology Co., Ltd.
 2020-07-01
all-trans-4-Oxoretinoic acid
 $74.00/1mg
VIP6Y
TargetMol Chemicals Inc.
2025-11-04
INQUIRY