ANP(1-28) Acetate (human, porcine) NEW
| Price | $1080 |
| Package | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-16 |
Product Details
| Product Name: ANP(1-28) Acetate (human, porcine) | CAS No.: 1366000-58-9 |
| Purity: 98.24% | Supply Ability: 10g |
| Release date: 2025/10/16 |
Product Introduction
Bioactivity
| Name | ANP(1-28) Acetate (human, porcine) |
| Description | Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate), a 28-amino acid hormone, is naturally produced and released by the human heart upon cardiac injury or mechanical stretch. This compound effectively inhibits the secretion of endothelin-1 in a dose-dependent manner. |
| In vitro | Atrial natriuretic peptide (ANP), isolated from mammalian hearts, exhibits diuretic, natriuretic, and vasodilatory properties. It has been observed that porcine ANP (1-28) not only inhibits the secretion of immunoreactive endothelin-1 in porcine endothelial cells and aorta upon stimulation with Angiotensin II (Ang II) but also elevates cellular cGMP levels. Similarly, human ANP (1-28) suppresses immunoreactive endothelin-1 secretion and enhances cyclic GMP in human umbilical-vein endothelial cells when stimulated by angiotensin II (ANGII) and thrombin. Moreover, in normal rat glomeruli, Human 125I-ANP (1-28) binds to high-affinity receptors, significantly increasing cGMP without affecting cAMP, showcasing its integral role in electrolyte and fluid homeostasis[1,2,3]. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 100 mg/mL (31.84 mM), Sonication is recommended. |
| Keywords | EndothelinReceptor | Endothelin Receptor | Carperitide Acetate | 89213-87-6 Free base | 89213-87-6 |
| Inhibitors Related | Macitentan | BMS 182874 | Bosentan | BMS 182874 hydrochloride | Sitaxsentan sodium | Edonentan | Sulfisoxazole | Ambrisentan | Aprocitentan | Sparsentan | Nebentan potassium | Clazosentan |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $80.00/1kg |
VIP3Y
|
Zibo Hangyu Biotechnology Development Co., Ltd
|
2023-11-01 | |
| $40.00/1kg |
Hebei Yanxi Chemical Co., Ltd.
|
2023-09-18 | ||
| $10.00/1kg |
Nantong Guangyuan Chemicl Co,Ltd
|
2023-11-14 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
INQUIRY