Antiparasitic agent-9 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: Antiparasitic agent-9 | CAS No.: 2516237-50-4 |
| Supply Ability: 10g | Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | Antiparasitic agent-9 |
| Description | Antiparasitic agent-9 (compound 47) is a highly effective and orally administered antiparasitic agent, demonstrating significant efficacy against the human parasite [1]. |
| In vivo | Antiparasitic agent-9 (compound 47) administered orally at 15 mg/kg twice daily for seven days significantly reduces the adult worm burden by 59% in the jird L. sigmodontis infection model. When given once at varying doses (2 mg/kg intravenously, 10 and 30 mg/kg orally), it shows a brain to plasma ratio of 0.08, indicating minimal brain penetration. In male CD-1 mice, a 30 mg/kg oral dose achieved a maximum concentration (C max) of 13.9 μM, an absorption time (T max) of 0.5 hours, and an area under the curve (AUC) from 0 to infinity of 121 μM·h. The compound demonstrated a clearance (CL) rate of 3.6 mL/min/kg, a steady-state volume of distribution (Vd ss) of 0.74 mL/kg, a bioavailability (F) of 57%, and an efflux ratio (ER) of 12, highlighting its pharmacokinetic properties. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | Picaridin | Flubendazole | Kojic acid | Urethane | Hydroxychloroquine | Metronidazole | Nitazoxanide | 2-Amino-2-methyl-1-propanol | Doxycycline | Fenpyroximate | Coumaran | Cloxiquine |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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