
B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated NEW
Price | $355 |
Package | 20μg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-19 |
Product Details
Product Name: B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Supply Ability: 10g |
Release date: 2025/07/19 |
Product Introduction
Bioactivity
Name | B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated |
Description | B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H4 consists of a 235 amino acid (aa) extracellular domain (ECD) with two Ig-like V-type domains, a 21 aa transmembrane segment, and a 2 aa cytoplasmic tail. It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation. |
Storage | Shipping with blue ice/Shipping at ambient temperature. |
Keywords | FLJ-22418 | FLJ 22418 | B7XPRO-1291 | B7XPRO 1291 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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