Bavisant dihydrochloride hydrate NEW
| Price | $89 | $789 | $1240 | 
| Package | 2mg | 50mg | 100mg | 
| Min. Order: | |
| Supply Ability: | 10g | 
| Update Time: | 2025-10-27 | 
Product Details
| Product Name: Bavisant dihydrochloride hydrate | CAS No.: 1103522-80-0 | 
| Supply Ability: 10g | Release date: 2025/10/27 | 
Product Introduction
Bioactivity
| Name | Bavisant dihydrochloride hydrate | 
| Description | Bavisant dihydrochloride hydrate (JNJ31001074AAC) is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action related to wakefulness and cognition, and it has potential as a treatment for ADHD. In a clinical trial, the mean change from baseline in the total ADHD-RS-IV score at day 42 was -8.8 in the placebo group versus -9.3, -11.2, and -12.2 in the bavisant 1 mg/day, 3 mg/day, and 10 mg/day groups, respectively; however, the change in the 10 mg/day group was not statistically superior to placebo (p=0.161). Statistical comparisons of the 1 mg/day and 3 mg/day groups with placebo based on a step-down closed testing procedure were not performed. Bavisant has completed a phase II ADHD trial, but no results have been reported [1]. Clinical trial: A Study to Characterize the Pharmacokinetics and Effect of Food on JNJ-31001074 in Healthy Volunteers. Phase 2. IC50 Value: Target: H3 receptor in vitro. | 
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | 
| Solubility Information | H2O : 50 mg/mL (118.94 mM), Sonication is recommended. DMSO : 1 mg/mL (2.38 mM), Sonication is recommended.  | 
| Keywords | Bavisant dihydrochloride hydrate | Bavisant dihydrochloride Hydrate | 
| Inhibitors Related | Chlorphenesin | Betahistine mesylate | Meclizine dihydrochloride | Mirtazapine | Lidocaine | Famotidine | Loratadine | Mebhydrolin napadisylate | Sodium butanoate | Alginic acid | Trazodone hydrochloride | Mianserin hydrochloride | 
Company Profile Introduction
                            Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
                        
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