Betaine chloride NEW
| Price | $42 | $98 |
| Package | 100mg | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-27 |
Product Details
| Product Name: Betaine chloride | CAS No.: 590-46-5 |
| Purity: ≥95% | Supply Ability: 10g |
| Release date: 2025/04/27 |
Product Introduction
Bioactivity
| Name | Betaine chloride |
| Description | Betaine chloride (Betaine hydrochloride) is an acidic form of betaine, a vitamin-like substance observed in grains and other foods; gains the amplification of DNA by decreasing the formation of secondary structure in GC-rich regions. |
| In vitro | Exposure to increasing levels of Betaine hydrochloride significantly inhibits HeLa cell proliferation, as demonstrated by the MTT assay (p<0.05). The S phase cell percentage is notably higher in groups exposed to doses below 5 mg/mL compared to those subjected to higher doses, whereas Sub-G1 phase rates exhibit the reverse trend (p<0.05). Concentrations of Betaine hydrochloride above 5.0 mg/mL markedly induce apoptosis in HeLa cells (p<0.01). Superoxide dismutase (SOD) activity in low dose groups slightly exceeds that of the control group (p<0.05). Additionally, there's a noticeable synchrony and correlation in the expression levels of pro-apoptotic genes (Bax, P53, Caspase 3) and the anti-apoptotic gene (Bcl-2). Furthermore, upon inducing apoptosis signals, p53 and cyclin D1 are activated, potentially halting the cell cycle at either the G1/S or S/G2 checkpoints. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 43 mg/mL (279.93 mM), Sonication is recommended. |
| Keywords | Inhibitor | inhibit | Glycine betaine-binding periplasmic protein | EndogenousMetabolite | Endogenous Metabolite | Circadian clock protein KaiB | Chloridechannel | Chloride channel | Betaine Hydrochloride | Betaine chloride | Betaine Chloride | Betaine |
| Inhibitors Related | Sucrose | Acetaminophen | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | L-Methionine | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Alkaloid Natural Product Library | EMA Approved Drug Library | Selected Plant-Sourced Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Microbial Natural Product Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Bioactive Compounds Library Max | Ion Channel Targeted Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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