Bintrafusp alfa NEW
| Price | $263 | $689 |
| Package | 1mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-09-17 |
Product Details
| Product Name: Bintrafusp alfa | CAS No.: 1918149-01-5 |
| Purity: 96.1% (SDS-PAGE); 99.2% (SEC-HPLC) | Supply Ability: 10g |
| Release date: 2025/09/17 |
Product Introduction
Bioactivity
| Name | Bintrafusp alfa |
| Description | Bintrafusp alfa (M7824) is a bifunctional fusion protein consisting of the extracellular structural domain of TGF-βRII (a TGF-β "trap") fused to a monoclonal antibody against human immunoglobulin G1 fused to programmed death ligand 1 (PD-L1), which is known for its anticancer activity, and can be used to study esophageal cancer. It has anticancer activity and can be used to study esophageal cancer. |
| In vitro | Bintrafusp alfa is capable of providing sustained protective immunity, reducing the function of regulatory T cells, significantly increasing the infiltration of CD8+ T cells and natural killer cells, while also decreasing the infiltration of bone marrow-derived suppressor cells within the tumor. [1] |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | TGFβRII | TGF-β/Smad | TGFβ | TGFbeta/Smad | TGF-beta | TGFbeta | TGF-b/Smad | TGFb | Smad |
| Inhibitors Related | SB-431542 | DMH-1 | Hydrochlorothiazide | Chromenone 1 | LY-364947 | BMP signaling agonist sb4 | Dorsomorphin | Pirfenidone | A 83-01 | Alantolactone | Pentabromophenol | Oxymatrine |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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