Product Details
| Product Name:
BRD4884 |
CAS No.:
1404559-91-6 |
| Purity:
99.19% |
Supply Ability:
10g |
| Release date:
2026/02/02 |
Product Introduction
Bioactivity
| Name | BRD4884 |
| Description | BRD4884 is a highly selective and efficient HDAC1 and HDAC2 inhibitor that also inhibits HDAC3, used in research on neurological disorders. |
| In vitro | BRD4884 is a potent HDAC inhibitor with IC50 values of 29 nM, 62 nM, and 1.09 µM for HDAC1, 2, and 3, respectively.
BRD4884 (10 μM for 24 hours) increased acetylation of histone H4K12 and H3K9 in mouse forebrain primary neuron cultures. [1] |
| In vivo | BRD4884 has a half-life of 0.9 hours in mice and has good brain permeability.
BRD4884 (10 and 1 mg/kg, intraperitoneal injection) salvaged memory deficits associated with P25-induced neurodegeneration in situational fear conditioning. [1] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 20 mg/mL (63.62 mM), Sonication and heating are recommended.
|
| Keywords | BRD4884 | BRD 4884 |
| Inhibitors Related | Valproic acid sodium salt | Panobinostat | Methoxyacetic acid | Sodium 4-phenylbutyrate | Acefylline | Manganese chloride (tetrahydrate) | Curcumin | Valproic Acid | Sodium butanoate | Theophylline | 4-Phenylbutyric acid | Methyl L-histidinate dihydrochloride |
| Related Compound Libraries | DNA Damage & Repair Compound Library | Histone Modification Compound Library | Bioactive Compound Library | Epigenetics Compound Library | Chromatin Modification Compound Library | Post-Translational Modification Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | High-Efficiency Gene Editing Small Molecule Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States