Product Details
| Product Name:
Brigimadlin |
CAS No.:
2095116-40-6 |
| Purity:
98.17% |
Supply Ability:
10g |
| Release date:
2025/10/20 |
Product Introduction
Bioactivity
| Name | Brigimadlin |
| Description | Brigimadlin (BI 907828) is an orally active and highly potent E3 ubiquitin-protein ligase
MDM2-p53 antagonist with antitumor activity.Brigimadlin can be used to study metastatic BTC, PDAC, lung adenocarcinoma, or bladder cancer. |
| In vitro | Brigimadlin (at concentrations ranging from 0-10 nM; over 48 hours) inhibits the proliferation of BT48, BT50, BT67, BT69, BT89, and BT94, with respective IC50 values of 58.5, 21.1, 37.9, 89.8, 16.7, and 46.8 pM[1]. |
| Storage | keep away from direct sunlight,store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | PSMA1007 | PSMA 1007 | p53 | MDM2 | Brigimadlin |
| Inhibitors Related | 10-Hydroxydecanoic Acid | Flubendazole | Rotenone | XI-006 | 2,5-Dihydroxybiphenyl | Thiabendazole | NSC232003 | Minocycline hydrochloride | Triglycidyl isocyanurate | C16 Ceramide | Indole-3-carbinol | Diethanolamine hydrochloride |
| Related Compound Libraries | Anti-Colorectal Cancer Compound Library | Glycometabolism Compound Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Orally Active Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library | Anti-Cancer Drug Library | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States