Broussonin E NEW
| Price | $61 | $147 |
| Package | 1mg | 5mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-27 |
Product Details
| Product Name: Broussonin E | CAS No.: 90902-21-9 |
| Purity: 99.86% | Supply Ability: 10g |
| Release date: 2026/07/27 |
Product Introduction
Bioactivity
| Name | Broussonin E |
| Description | Broussonin E is a natural phenolic compound belonging to the class of polyphenolic secondary metabolites. It inhibits inflammation by suppressing ERK and p38 MAPK, enhancing the JAK2-STAT3 signaling pathway, and regulating the activation state of macrophages. Broussonin E exhibits antioxidant, anti-inflammatory, and tyrosinase-inhibitory activities and is commonly used in research on natural medicines and skin biology. |
| In vitro | Broussonin E (20 μM, 3 h) inhibits LPS (lipopolysaccharides)-stimulated phosphorylation of ERK and p38 MAPK[1]. Broussonin E activates Janus kinase (JAK) 2 and signal transduction and transcription activator (STAT) 3[1]. Broussonin E (0–20 μM, 3 h) inhibits LPS-induced pro-inflammatory production in RAW264.7 cells, including TNF-α, IL-1β, IL-6, COX-2, and iNOS[1]. Broussonin E enhances the expression of anti-inflammatory mediators such as IL-10, CD206, and arginase-1 (Arg-1) in LPS-stimulated RAW264.7 cells [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80 mg/mL (277.45 mM), Sonication is recommended. |
| Keywords | TNF-α | STAT | p38MAPK | p38 MAPK | JAK | ERK | Broussonin E |
| Inhibitors Related | Flubendazole | Urea | L-Cysteine | Gum arabic | Acetaminophen | Triphenyl phosphate | D-Psicose | 5-Aminosalicylic Acid | Guaiacol | Trometamol | Gluconate Calcium | Gluconate sodium |
| Related Compound Libraries | Selected Plant-Sourced Compound Library | Natural Product Library for HTS |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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