Calcineurin A/PPP3CA Protein, Human, Recombinant (His) NEW
| Price | $696 |
| Package | 50μg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-29 |
Product Details
| Product Name: Calcineurin A/PPP3CA Protein, Human, Recombinant (His) | Supply Ability: 10g |
| Release date: 2025/08/29 |
Product Introduction
Bioactivity
| Name | Calcineurin A/PPP3CA Protein, Human, Recombinant (His) |
| Description | PPP3CA, also known as protein phosphatase 2B, is a member of the PPP phosphatase family, PP-2B subfamily. It is the alpha catalytic subunit of protein phosphatase 2B (PP2B). PP2B is a holoenzyme that is comprised of a catalytic subunit associated with regulatory subunits. It is a calcium regulated enzyme that is activated by calmodulin and participates in the signaling cascades involved in development of the nervous, cardiovascular, and musculoskeletal systems. PPP3CA activates the T cells of the immune system and can be blocked by drugs. It also activates NFATc (a transcription factor) by dephosphorylating it. The activated NFATc is subsequently translocated into the nucleus, where it upregulates the expression of interleukin 2. PPP3CA interacts with CRTC2, MYOZ1, MYOZ2 and MYOZ3. It also interacts with DNM1L. The interaction dephosphorylates DNM1L and regulates its translocation to mitochondria. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | CNA-1 | CNA 1 | CCN-1 | CCN 1 | CALNA-1 | CALNA 1 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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United States