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Postion:Product Catalog >Organic Chemistry>Carboxylic acids and derivatives>Acyclic carboxylic acid>Citric acid
Citric acid
  • Citric acid

Citric acid NEW

Price $44
Package 1mL
Min. Order:
Supply Ability: 10g
Update Time: 2025-10-03

Product Details

Product Name: Citric acid CAS No.: 77-92-9
Purity: 98.88% Supply Ability: 10g
Release date: 2025/10/03

Product Introduction

Bioactivity

NameCitric acid
DescriptionCitric acid (Citro) is a weak organic tricarboxylic acid found in citrus fruits. Citric acid is a food additive and a natural preservative.
In vitroMETHODS: HaCaT cells were treated with Citric acid (0-12.5 mM) for 24 hours, and the percentage of viable cells was determined by flow cytometry. RESULTS: Citric acid exhibited anti-proliferative activity in a dose-dependent manner. [1] METHODS: HaCaT cells were treated with Citric acid (12.5 mM) for 48 hours, and the levels of related proteins were detected by western blot. RESULTS: Citric acid increased the expressions of FAS, BAX, BID, AIF, EndoG, cytochrome C, PARP, GADD153, GRP78 and Caspase-3, -8, -9, and decreased the expressions of BCL-2 and BCL-Xl. [1]
In vivoMETHODS: To study the effect of Citric acid on the liver of mice, Citric acid (120, 240, and 480 mg/kg) was intraperitoneally injected into mice. RESULTS: Citric acid significantly reduced the activity of GSH-Px in the liver of mice, induced an increase in the level of MDA (malondialdehyde), and increased the activity of caspase-3 to induce apoptosis in a dose-dependent manner. [2] METHODS: To study the nephrotoxicity of Citric acid, Citric acid (120, 240, and 480 mg/kg) was intraperitoneally injected into mice every week for 3 consecutive weeks. RESULTS: Citric acid causes nephrotoxicity in mice. [3]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationH2O : 100 mg/mL (520.51 mM), Sonication is recommended.
DMSO : 240 mg/mL (1249.22 mM), Sonication is recommended.
KeywordsS phase | renal toxicity | Oxidative damage | MDA levelsm | Inhibitor | inhibit | HaCaT cells | G2/M phase | EndogenousMetabolite | Endogenous Metabolite | Citric acid | Bacterial | Apoptosis | antioxidative | Antibiotic
Inhibitors RelatedSucrose | Neomycin sulfate | Cysteamine hydrochloride | Sulfamethoxazole sodium | Terbinafine hydrochloride | Daidzein | Tributyrin | Ferulic Acid | Glycerol | Thymidine | Dimethyl sulfoxide | 3-Indoleacetic acid
Related Compound LibrariesAnti-Tumor Natural Product Library | Traditional Chinese Medicine Monomer Library | Selected Plant-Sourced Compound Library | Anti-Cancer Clinical Compound Library | Miao medicine Compound Library | Tobacco Monomer Library | FDA-Approved Drug Library | Anti-infective Natural Product Library | Cosmetic Ingredient Compound Library | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Gut Microbial Metabolite Library | Ancient Chinese Classical Formulas Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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