Cyproheptadine NEW
| Price | Get Latest Price |
| Package | 1removed |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-06 |
Product Details
| Product Name: Cyproheptadine | CAS No.: 129-03-3 |
| Supply Ability: 10g | Release date: 2025/11/06 |
Product Introduction
Bioactivity
| Name | Cyproheptadine |
| Description | Cyproheptadine is an orally active serotonin 5-HT2A receptor antagonist with multiple pharmacological properties including antidepressant, anti-serotonin, antiplatelet, and antithrombotic effects. Cyproheptadine is used as a research compound for investigating thromboembolic diseases, serotonergic signaling, and potential links between serotonin modulation and metabolic disorders such as diabetes. |
| In vitro | In in vitro experiments, Cyproheptadine (0.01–100 nM, 1 minute) dose-dependently inhibited serotonin-enhanced ADP-induced mouse platelet aggregation [2]; at a concentration of 10 nM, Cyproheptadine suppressed 15 μM serotonin-potentiated 1 μM ADP-induced platelet tyrosine phosphorylation [2]; Cyproheptadine also inhibited activation markers of homo sapiens platelets, including phosphatidylserine (PS) exposure (detected by annexin V), P-selectin (CD62P), and the GPIIb-IIIa complex (assessed via PAC-1 binding) [2]. |
| In vivo | Cyproheptadine (1 mg/kg, intraperitoneal injection, once daily for 5 consecutive days) significantly prolonged the arterial occlusion time and tail bleeding time in C57BL/6 mice [2]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | Alverine citrate | Sevoflurane | Dapoxetine hydrochloride | Cefaclor monohydrate | Clozapine N-Oxide | Mirtazapine | 1,8-Cineole | Venlafaxine hydrochloride | Cloperastine hydrochloride | Trazodone hydrochloride | Mianserin hydrochloride | Cinchonidine |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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