D5D-IN-326 NEW
| Price | $1430 | $1860 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: D5D-IN-326 | CAS No.: 1236767-85-3 |
| Supply Ability: 10g | Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | D5D-IN-326 |
| Description | D5D-IN-326 is an orally active delta-5 desaturase (D5D) inhibitor (IC50s: 72 and 22 nM for rat and human D5D in enzymic and cell-based assays). It has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and decreases body weight in diet-induced obese C57BL/6J mice. |
| In vivo | D5D-IN-326 administered orally at a dose of 10 mg/kg for six weeks notably reduces the gene expression levels of Ccl2, Cd68, Adgre1, and Il6, as well as epididymal Lep and Adipoq mRNAs, which are significantly elevated in mice with diet-induced obesity (DIO) following a high-fat diet (HFD). Additionally, at a dosage of 10 mg/kg, D5D-IN-326 progressively decreases body weight over the same period. However, lower doses (0.1 and 1 mg/kg) prove ineffective in altering body weight or addressing DIO in mice after six weeks of treatment. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Rat D5D | Human D5D | D5D-IN-326 | D5D-IN326 | D-5D-IN-326 | D5DIN326 | D5D-IN 326 | D5D IN 326 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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