Product Details
| Product Name:
DOTMA |
CAS No.:
104872-42-6 |
| Purity:
99.72% |
Supply Ability:
10g |
| Release date:
2026/01/04 |
Product Introduction
Bioactivity
| Name | DOTMA |
| Description | DOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) is a tetra-methylated DOTA analogue. DOTMA is a cationic lipid and can be used as a non-viral vector for gene therapy. It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro. It exhibits effective in vitro and in vivo gene transfection. DOTMA induces a positive charge on the liposomes and thus promotes efficient liposome- cell membrane interaction. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility Information | DMSO : 45 mg/mL (67.11 mM), Sonication and heating to 60℃ are recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (2.98 mM), Sonication is recommended.
|
| Keywords | DOTMA | Cationic Lipid |
| Inhibitors Related | Stearamide | DOTAP chloride | DODAP | 1,2-dioleoyl-sn-glycero-3-phosphocholine | DPPC | 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC | D-Lin-MC3-DMA | Benzyl nicotinate | ALC-0315 | DSPS | Cholesterol | Phosphatidylcholines,soya |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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