Droloxifene NEW
| Price | $49 | $118 | $178 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-24 |
Product Details
| Product Name: Droloxifene | CAS No.: 82413-20-5 |
| Purity: 99.27% | Supply Ability: 10g |
| Release date: 2025/10/24 |
Product Introduction
Bioactivity
| Name | Droloxifene |
| Description | Droloxifene (3-Hydroxytamoxifen), a tamoxifen derivative, is an oral active and selective estrogen receptor modulator.Droloxifene induced p53 expression and apoptosis in McF-7 cells.Fluroxifene has anti-estrogen and anti-implantation effects.Fluroxifene prevented bone loss in ovariectomized rats. |
| In vitro | Droloxifene induces apoptosis in MCF-7 cells(10 nM; 16-18 hours)[1]. |
| In vivo | Droloxifene (5-20 mg/kg,P.o.;Daily for 4 weeks can bring THE BMD of DFM up to 10mg/kg and completely prevent OVX from reducing the BMC and BMD of DFM at 20mg /kg/day[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 40 mg/mL (103.22 mM), Sonication is recommended. |
| Keywords | EstrogenReceptor | Estrogen Receptor | estrogen receptor | ERR | Droloxifene |
| Inhibitors Related | Stavudine | Cysteamine hydrochloride | Sodium 4-phenylbutyrate | Metronidazole | Citric Acid Triammonium | Tributyrin | L-Methionine | Sodium citrate | Cystamine dihydrochloride | L-Ascorbic acid sodium salt | Alginic acid | Dextran sulfate sodium salt (MW 5000) |
| Related Compound Libraries | Nuclear Receptor Compound Library | Apoptosis Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Anti-Breast Cancer Compound Library | Anti-Ovarian Cancer Compound Library | Endocrinology-Hormone Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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United States