(E)-5-(2-Bromovinyl)uracil NEW
| Price | $158 | $265 | $488 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-27 |
Product Details
| Product Name: (E)-5-(2-Bromovinyl)uracil | CAS No.: 69304-49-0 |
| Supply Ability: 10g | Release date: 2025/07/27 |
Product Introduction
Bioactivity
| Name | (E)-5-(2-Bromovinyl)uracil |
| Description | (E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU), which can be regenerated to BVDU in vivo. BVU irreversibly inactivates dihydropyrimidine dehydrogenase (DPD) in an NADPH-dependent manner, enhancing the efficacy of the chemotherapeutic agent and DPD substrate 5-fluorouracil in a P388 murine leukemia model when administered at a dose of 200 μmol/kg, thereby increasing survival time. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMF : 60 mg/mL (276.47 mM), Sonication is recommended. PBS (pH 7.2) : 8 mg/mL (36.86 mM), Sonication is recommended. DMSO : 53 mg/mL (244.22 mM), Sonication is recommended. Ethanol : 0.8 mg/mL (3.69 mM), Sonication is recommended. |
| Keywords | (E) 5 (2 Bromovinyl)uracil | (E)5(2Bromovinyl)uracil | 5-(2-Bromovinyl)uracil |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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