Eact NEW
| Price | $31 | $72 | $128 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-13 |
Product Details
| Product Name: Eact | CAS No.: 461000-66-8 |
| Purity: 98.62% | Supply Ability: 10g |
| Release date: 2026/07/13 |
Product Introduction
Bioactivity
| Name | Eact |
| Description | Eact is a selective and potent TMEM16A activator that directly activates the TRPV1 channels in sensory nociceptors, thereby producing itch, acute nociception, and thermal hypersensitivity (brackets). |
| In vitro | Eact activates membrane currents in mTRPV1-expressing HEK293T cells in a concentration-dependent manner (EC50: 11.6 ± 2.5 μM). Eact induces both itch-and pain- related behaviours in a TRPV1-dependent manner. TMEM16A activator Eact activates both native and recombinant TRPV1 channels[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 125 mg/mL (291.72 mM), Sonication is recommended. 10% DMSO+90% Saline : < 10 mg/mL (23.34 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (23.34 mM), Suspension. H2O : Insoluble 10% DMSO+90% Corn Oil : 2.5 mg/mL (5.83 mM), Sonication is recommended. |
| Keywords | TMEM16A | Inhibitor | inhibit | Eact | Cl? Channels | Chloridechannel | Chloride channel |
| Inhibitors Related | Selamectin | Niflumic acid | Urethane | Lubiprostone | Halothane | Betaine chloride | Afoxolaner | Fenamic acid | T16Ainh-A01 | Meticrane | Phenyl benzoate | Adjudin |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36 Washington Street, Wellesley Hill, MA
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