Endosidin 7 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-09 |
Product Details
| Product Name: Endosidin 7 | CAS No.: 329072-88-0 |
| Purity: 99.65% | Supply Ability: 10g |
| Release date: 2025/11/09 |
Product Introduction
Bioactivity
| Name | Endosidin 7 |
| Description | Endosidin 7, a specific inhibitor of callose synthase, organizes callose deposition during plant cytoplasmic division without affecting endosomal transport during interphase or cytoskeletal organization, preventing late cytokinesis. |
| In vitro | Endosidin 7 (ES7) inhibits Arabidopsis callose synthase activity in a concentration-dependent manner using CHAPS-extracted membrane fractions. At 100 μM, ES7 reduces enzyme activity by approximately 50%. Enzyme kinetics indicate that ES7 acts as a mixed-type inhibitor, increasing the apparent Km and decreasing the Vmax, suggesting interaction with both the free enzyme and the enzyme–substrate complex at different affinities[1]. |
| In vivo | Endosidin 7 effectively arrests late cytokinesis in Arabidopsis seedlings. Root growth assays determined an IC₅₀ of 4.8 μM. A 2-hour treatment with 25–50 μM Endosidin 7 induces cell plate fragmentation, binucleate cells, and complete inhibition of callose deposition at the cell plate. Endosidin 7 specifically targets late cytokinesis without affecting interphase endomembrane markers or cellulose biosynthesis[1]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Endosidin7 | Endosidin 7 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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