Finasteride acetate NEW
| Price | $2140 | $2785 | $3520 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: Finasteride acetate | CAS No.: 222989-99-3 |
| Supply Ability: 10g | Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | Finasteride acetate |
| Description | Finasteride (MK-906) acetate is a potent and competitive 5α-reductase inhibitor with an IC50 of 4.2 nM for type II 5α-reductase, demonstrating approximately 100-fold higher affinity for type II than type I. Finasteride acetate can be used for research on benign prostatic hyperplasia (BPH) and androgenic alopecia [1] [2] [3]. |
| In vitro | Finasteride, at a concentration of 10 μM over incubation periods of 6 to 24 hours, induces the expression of HO-1 and Nrf2 proteins in PC-3 cells, and also inhibits the conversion of [3 H]testosterone (T) to [3 H]dihydrotestosterone (DHT) in P. crustosum. In cell viability assays involving PC-3, DU-145, and LNCaP cell lines treated with finasteride at 10 μM for durations of 6, 12, and 24 hours, there was a noticeable increase in HO-1 protein expression in a time-dependent manner specifically in PC-3 cells. Additionally, finasteride triggered the expression of Nrf2 protein in DU-145 and PC-3 cells, though not in LNCaP cells. |
| In vivo | Finasteride, administered orally at a dosage of 0.1-0.5 mg/kg once daily for 16 weeks, effectively reduces prostatic size in male dogs aged 2.7-11 years and weighing 10.3-49 kg with spontaneous benign prostatic hyperplasia (BPH), as indicated by a decrease in prostatic diameter (20%), volume (43%), and serum dihydrotestosterone (DHT) concentration (58%). This treatment does not negatively impact semen quality or serum testosterone levels and is free from adverse effects on the animals [3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Finasteride acetate | Finasteride Acetate |
| Inhibitors Related | MK 0434 | Epalrestat | 2-Chloro-1-(4-fluorobenzyl)benzimidazole | Lapisteride | Lidorestat | IDD388 | Alpha-Estradiol | Finasteride | Isoliquiritigenin | Ranirestat | Kopexil | Dutasteride |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
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